Passerini-Glazel Feminizing Genitoplasty: Modifications in 17 Years of Experience with 82 Cases

Arianna Lesma, Aldo Bocciardi, Francesco Montorsi, Patrizio Rigatti

Research output: Contribution to journalArticlepeer-review


Objectives: To describe modifications of Passerini-Glazel feminizing genitoplasty and report on long-term functional outcome. Methods: Modifications include vaginal dissection and disconnection from the urethrovaginal sinus as the initial stage of the procedure; large dissection of the neurovascular bundle on both dorsal and lateral faces of the clitoris; plication of the skin around the reduced clitoris; and suturing the lateral edge of the proximal portion of the mucocutaneous plate with the labia majora's medial edge to a plane deeper than the subcutaneous tissue. These modifications reduce bleeding and operating time, better preserve clitoral sensitivity, form the clitoral prepuce, and create labia minora. Results: Eighty-two patients underwent modified Passerini-Glazel feminizing genitoplasty. Mean operating time was 120 min (range: 100-180). Forty-six patients (46 of 82, 56%) were assessed at a mean follow-up of 5 yr (range: 2-9). There were no cases of clitoral vascularization defect or urethrovaginal fistula. The urethral meatus was never hypospadic. The vaginal introitus was large and elastic in all cases. Vaginal caliber at the internal suture line was as large as the vaginal introitus and the distal native vagina in 20 (43.5%) of the 46 girls. All mothers and patients reported satisfaction with external genital appearance. Conclusions: These long-term results suggest that our modifications of one-stage Passerini-Glazel feminizing genitoplasty facilitate the procedure and produce good cosmetic results.

Original languageEnglish
Pages (from-to)1638-1644
Number of pages7
JournalEuropean Urology
Issue number6
Publication statusPublished - Dec 2007


  • Congenital adrenal hyperplasia
  • Feminization
  • Intersexuality

ASJC Scopus subject areas

  • Urology


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