Pathobiology of ALK-negative anaplastic large cell lymphoma

Stefano A. Pileri, Claudio Agostinelli, Francesco Bacci, Elena Sabattini, Carlo Sagramoso, Brunangelo Falini, Pier Paolo Piccaluga

Research output: Contribution to journalArticlepeer-review


The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presented.

Original languageEnglish
Article numbere5
Pages (from-to)8-10
Number of pages3
JournalPediatric Reports
Issue number2S
Publication statusPublished - 2011


  • ALK-negative
  • Anaplastic
  • Cell
  • Large
  • Lymphoma

ASJC Scopus subject areas

  • Pediatrics


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