Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: A European consensus statement

Christian G. Bien, T. Granata, C. Antozzi, J. H. Cross, O. Dulac, M. Kurthen, H. Lassman, R. Mantegazza, J. G. Villemure, R. Spreafico, C. E. Elger

Research output: Contribution to journalArticle

Abstract

Rasmussen encephalitis (RE) is a rare but severe immune-mediated brain disorder leading to unilateral hemispheric atrophy, associated progressive neurological dysfunction and intractable seizures. Recent data on the pathogenesis of the disease, its clinical and paraclinical presentation, and therapeutic approaches are summarized. Based on these data, we propose formal diagnostic criteria and a therapeutic pathway for the management of RE patients.

Original languageEnglish
Pages (from-to)454-471
Number of pages18
JournalBrain
Volume128
Issue number3
DOIs
Publication statusPublished - Mar 2005

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Keywords

  • Diagnostic criteria
  • Encephalitis
  • Epilepsy
  • Pathophysiology
  • Therapy

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Bien, C. G., Granata, T., Antozzi, C., Cross, J. H., Dulac, O., Kurthen, M., Lassman, H., Mantegazza, R., Villemure, J. G., Spreafico, R., & Elger, C. E. (2005). Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: A European consensus statement. Brain, 128(3), 454-471. https://doi.org/10.1093/brain/awh415