Pathogenesis of uncus deformation and vertebral artery compression: Histologic investigations of the uncus and dynamic angiography of the vertebral artery in the cadaveric cervical spine

Francesco Benazzo, Alberto Araujo Alvare, Darcio Nalli, Alberto Pio, Jose Laredo Filho

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Twenty-one cervical spines were collected from fresh cadavers (12 male, nine female), their ages ranging from 10 to 90 years (mean 49.47). After removing muscle debris from the spines, they were mounted and tested on a device to passively reproduce the main movements of the spine. The degree of motion in flexion-extension and lateral bending significantly decreased from group A (ages 10-49 years) to group B (51-90 years) (p <0.005) and was directly correlated with the amount of cervical spine degenerative alterations. The incidence of these alterations, classified according to Lysell (1969), was highest at C5-6. On the testing machine, dynamic angiography of the vertebral artery showed an impingement with extrinsic compression of the vessels in four of 28 successful injections. The histologic serial sections of the uncus showed a characteristic pattern of ossification-deformation: a newly formed cartilaginous tissue tipping the apex of the uncus, forming a double protruding contour of the apex, rapidly ossifying, and appearing to deform outward together with the disk degeneration and consequently decreasing in height.

Original languageEnglish
Pages (from-to)111-119
Number of pages9
JournalJournal of Spinal Disorders
Volume7
Issue number2
Publication statusPublished - 1994

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Vertebral Artery
Angiography
Spine
Intervertebral Disc Degeneration
Cadaver
Osteogenesis
Age Groups
Equipment and Supplies
Muscles
Injections
Incidence

Keywords

  • Cartilage
  • Uncus
  • Vertebral artery impingement

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Pathogenesis of uncus deformation and vertebral artery compression : Histologic investigations of the uncus and dynamic angiography of the vertebral artery in the cadaveric cervical spine. / Benazzo, Francesco; Araujo Alvare, Alberto; Nalli, Darcio; Pio, Alberto; Laredo Filho, Jose.

In: Journal of Spinal Disorders, Vol. 7, No. 2, 1994, p. 111-119.

Research output: Contribution to journalArticle

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