Abstract
This study provides a guideline to a dynamic approach toward the diagnosis of hepatocellular carcinoma (HCC). Bile production, fibrinogen synthesis, Mallory body, fibrinogen ground-glass and abnormal glycogen bodies as a reflection of 'clone' selection, and hepatitis B virus (HBV) antigen expression in tumor cells can be considered as markers for the morphological diagnosis of HCC. The demonstration in tumor cells of these diagnostic features requires a careful screening of routinely stained preparations in search of suggestive, characteristic, specific, or pathognomonic features further supplemented by ancillary techniques, such as histochemistry, immunocytochemistry, and electron microscopy.
Original language | English |
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Pages (from-to) | 168-169 |
Number of pages | 2 |
Journal | Journal of Surgical Oncology |
Volume | 53 |
Issue number | SUPPL. 3 |
Publication status | Published - 1993 |
Keywords
- hepatocellular carcinoma
- immunohistochemistry
- pathology
ASJC Scopus subject areas
- Medicine(all)
- Oncology
- Surgery