Pathology of hepatocellular carcinoma

Francesco Callea, Maurizio Favret, Carla Marino, Massimo Brisigotti

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This study provides a guideline to a dynamic approach toward the diagnosis of hepatocellular carcinoma (HCC). Bile production, fibrinogen synthesis, Mallory body, fibrinogen ground‐glass and abnormal glycogen bodies as a reflection of “clone” selection, and hepatitis B virus (HBV) antigen expression in tumer cells can be considered as markers for the morphological diagnosis of HCC. The demonstration in tumor cells of these diagnostic features requires a careful screening of routinely stained preparations in search of suggestive, characteristic, specific, or pathognomonic features further supplemented by ancillary techniques, such as histochemistry, immunocytochemistry, and electron microscopy. © 1993 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)168-169
Number of pages2
JournalJournal of Surgical Oncology
Volume53
Issue number3 S
DOIs
Publication statusPublished - 1993

Fingerprint

Hepatocellular Carcinoma
Abnormal Fibrinogens
Mallory Bodies
Pathology
Hepatitis B Antigens
Glycogen
Hepatitis B virus
Bile
Fibrinogen
Electron Microscopy
Clone Cells
Immunohistochemistry
Guidelines
Neoplasms

Keywords

  • hepatocellular carcinoma
  • immunohistoehemistry
  • pathology

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Pathology of hepatocellular carcinoma. / Callea, Francesco; Favret, Maurizio; Marino, Carla; Brisigotti, Massimo.

In: Journal of Surgical Oncology, Vol. 53, No. 3 S, 1993, p. 168-169.

Research output: Contribution to journalArticle

Callea, F, Favret, M, Marino, C & Brisigotti, M 1993, 'Pathology of hepatocellular carcinoma', Journal of Surgical Oncology, vol. 53, no. 3 S, pp. 168-169. https://doi.org/10.1002/jso.2930530544
Callea, Francesco ; Favret, Maurizio ; Marino, Carla ; Brisigotti, Massimo. / Pathology of hepatocellular carcinoma. In: Journal of Surgical Oncology. 1993 ; Vol. 53, No. 3 S. pp. 168-169.
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