Pathophysiologic aspects in severe head injury

Research output: Contribution to journalArticlepeer-review


Traumatic brain injuries (TBI) may be classified according to manifestation time (primary and secondary lesions) or to anatomical extent (focal and extended lesions). In both cases there are specific cellular, subcellular, metabolic, molecular variations, which are to be known in order to set up proper pharmacological and rehabilitative treatments. The Author aims at offering an up-to-date review of the most important patophysiologic mechanisms which take place after a severe brain injury.

Original languageEnglish
Pages (from-to)19-26
Number of pages8
JournalSAGGI - Child Development and Disabilities
Issue number2
Publication statusPublished - 2003


  • Diffuse axonal injury
  • Pathophysiologic mechanisms
  • Traumatic brain injury

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Rehabilitation
  • Neuropsychology and Physiological Psychology


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