Abstract
Although during the past two decades there has been considerable progress in the understanding of the pathophysiology of human essential hypertension, the basic mechanisms responsible for the development and progression of the disease still remain largerly undefined. This also applies to the pathophysiology of hypertension in women, although a number of haemodynamic, vascular, metabolic and neurohumoral factors have been identified throughout the years as being characterized by a gender-specific relation. This paper will examine the main differences in the haemodynamic, vascular, metabolic and neurohumoral profile characterizing normotensive as well as hypertensive females as compared with age-matched males. Although in some instances clearcut differences between genders can be found, overall the pathophysiological picture of the hypertensive state does not seem to have significant differences in men and women, at least up to the years when the menopausal-related hormonal changes take place.
| Original language | English |
|---|---|
| Journal | Journal of Hypertension |
| Volume | 20 |
| Issue number | SUPPL. 2 |
| DOIs | |
| Publication status | Published - May 2002 |
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Keywords
- Arterial distensibility
- Blood pressure
- Hemodynamics
- Hormones
- Sympathetic tone
ASJC Scopus subject areas
- Endocrinology
- Internal Medicine
Cite this
Pathophysiological aspects of hypertensive disease in women. / Grassi, Guido; Seravalle, Gino; Stella, Maria Luisa; Mancia, Giuseppe.
In: Journal of Hypertension, Vol. 20, No. SUPPL. 2, 05.2002.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pathophysiological aspects of hypertensive disease in women
AU - Grassi, Guido
AU - Seravalle, Gino
AU - Stella, Maria Luisa
AU - Mancia, Giuseppe
PY - 2002/5
Y1 - 2002/5
N2 - Although during the past two decades there has been considerable progress in the understanding of the pathophysiology of human essential hypertension, the basic mechanisms responsible for the development and progression of the disease still remain largerly undefined. This also applies to the pathophysiology of hypertension in women, although a number of haemodynamic, vascular, metabolic and neurohumoral factors have been identified throughout the years as being characterized by a gender-specific relation. This paper will examine the main differences in the haemodynamic, vascular, metabolic and neurohumoral profile characterizing normotensive as well as hypertensive females as compared with age-matched males. Although in some instances clearcut differences between genders can be found, overall the pathophysiological picture of the hypertensive state does not seem to have significant differences in men and women, at least up to the years when the menopausal-related hormonal changes take place.
AB - Although during the past two decades there has been considerable progress in the understanding of the pathophysiology of human essential hypertension, the basic mechanisms responsible for the development and progression of the disease still remain largerly undefined. This also applies to the pathophysiology of hypertension in women, although a number of haemodynamic, vascular, metabolic and neurohumoral factors have been identified throughout the years as being characterized by a gender-specific relation. This paper will examine the main differences in the haemodynamic, vascular, metabolic and neurohumoral profile characterizing normotensive as well as hypertensive females as compared with age-matched males. Although in some instances clearcut differences between genders can be found, overall the pathophysiological picture of the hypertensive state does not seem to have significant differences in men and women, at least up to the years when the menopausal-related hormonal changes take place.
KW - Arterial distensibility
KW - Blood pressure
KW - Hemodynamics
KW - Hormones
KW - Sympathetic tone
UR - http://www.scopus.com/inward/record.url?scp=0036563320&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036563320&partnerID=8YFLogxK
U2 - 10.1097/00004872-200212000-00001
DO - 10.1097/00004872-200212000-00001
M3 - Article
C2 - 12183855
AN - SCOPUS:0036563320
VL - 20
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
IS - SUPPL. 2
ER -