Abstract
Background: Depending on the length of the segment of columnar epithelium in the distal oesophagus, Barrett's oesophagus can be divided into long-segment and short-segment Barrett's oesophagus. This article describes the pathophysiological characteristics of both forms of Barrett's oesophagus. Methods: Review of the literature. Results: Although there is some disagreement, ours and most other studies suggest that long-segment columnar-lined oesophagus is causally linked to chronic gastro-oesophageal reflux and that this from of Barrett's oesophagus is characterized by lower oesophageal sphincter tone, reduced oesophageal contractility and increased acid reflux. Short-segment Barrett's oesophagus is also associated with acid reflux, but the degree of oesophageal acid exposure and the level of other pathophysiological alterations seem to be lower. Conclusion: Pathophysiological abnormalities appear to be more prominent in long-segment Barrett's oesophagus than in short-segment Barrett's oesophagus.
| Original language | English |
|---|---|
| Pages (from-to) | 40-43 |
| Number of pages | 4 |
| Journal | Scandinavian Journal of Gastroenterology, Supplement |
| Volume | 38 |
| Issue number | 239 |
| Publication status | Published - 2003 |
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Keywords
- Barrett's oesophagus
- Oesophageal manometry
- Oesophageal pH-monitoring
ASJC Scopus subject areas
- Gastroenterology
Cite this
Pathophysiological Characteristics of Long- and Short-Segment Barrett's Oesophagus. / Zentilin, P.; Reglioni, S.; Savarino, V.
In: Scandinavian Journal of Gastroenterology, Supplement, Vol. 38, No. 239, 2003, p. 40-43.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pathophysiological Characteristics of Long- and Short-Segment Barrett's Oesophagus
AU - Zentilin, P.
AU - Reglioni, S.
AU - Savarino, V.
PY - 2003
Y1 - 2003
N2 - Background: Depending on the length of the segment of columnar epithelium in the distal oesophagus, Barrett's oesophagus can be divided into long-segment and short-segment Barrett's oesophagus. This article describes the pathophysiological characteristics of both forms of Barrett's oesophagus. Methods: Review of the literature. Results: Although there is some disagreement, ours and most other studies suggest that long-segment columnar-lined oesophagus is causally linked to chronic gastro-oesophageal reflux and that this from of Barrett's oesophagus is characterized by lower oesophageal sphincter tone, reduced oesophageal contractility and increased acid reflux. Short-segment Barrett's oesophagus is also associated with acid reflux, but the degree of oesophageal acid exposure and the level of other pathophysiological alterations seem to be lower. Conclusion: Pathophysiological abnormalities appear to be more prominent in long-segment Barrett's oesophagus than in short-segment Barrett's oesophagus.
AB - Background: Depending on the length of the segment of columnar epithelium in the distal oesophagus, Barrett's oesophagus can be divided into long-segment and short-segment Barrett's oesophagus. This article describes the pathophysiological characteristics of both forms of Barrett's oesophagus. Methods: Review of the literature. Results: Although there is some disagreement, ours and most other studies suggest that long-segment columnar-lined oesophagus is causally linked to chronic gastro-oesophageal reflux and that this from of Barrett's oesophagus is characterized by lower oesophageal sphincter tone, reduced oesophageal contractility and increased acid reflux. Short-segment Barrett's oesophagus is also associated with acid reflux, but the degree of oesophageal acid exposure and the level of other pathophysiological alterations seem to be lower. Conclusion: Pathophysiological abnormalities appear to be more prominent in long-segment Barrett's oesophagus than in short-segment Barrett's oesophagus.
KW - Barrett's oesophagus
KW - Oesophageal manometry
KW - Oesophageal pH-monitoring
UR - http://www.scopus.com/inward/record.url?scp=1642456628&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1642456628&partnerID=8YFLogxK
M3 - Article
C2 - 14743882
AN - SCOPUS:1642456628
VL - 38
SP - 40
EP - 43
JO - Scandinavian Journal of Gastroenterology, Supplement
JF - Scandinavian Journal of Gastroenterology, Supplement
SN - 0085-5928
IS - 239
ER -