Pathophysiology of non alcoholic fatty liver disease

Salvatore Petta; Amalia Gastaldelli; Eleni Rebelos; Elisabetta Bugianesi; Piergiorgio Messa; Luca Miele; Gianluca Svegliati-Baroni; Luca Valenti; Ferruccio Bonino

doi:10.3390/ijms17122082

Pathophysiology of non alcoholic fatty liver disease

Salvatore Petta, Amalia Gastaldelli, Eleni Rebelos, Elisabetta Bugianesi, Piergiorgio Messa, Luca Miele, Gianluca Svegliati-Baroni, Luca Valenti, Ferruccio Bonino

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Review article › peer-review

Abstract

The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathophysiological interplay among major circulating effectors/mediators of fatty liver, such as circulating lipids, mediators released by adipose, muscle and liver tissues and pancreatic and gut hormones in relation to diet, exercise and inflammation.

Original language	English
Article number	2082
Journal	International Journal of Molecular Sciences
Volume	17
Issue number	12
DOIs	https://doi.org/10.3390/ijms17122082
Publication status	Published - Dec 11 2016

Keywords

Adiponectin
Cholesterol
Fatty liver
Free fatty acids
Ghrelin
Glucagon
Glucagon-like peptide 1
Insulin
Insulin resistance
Irisin
Leptin
Selenoprotein P

ASJC Scopus subject areas

Catalysis
Molecular Biology
Computer Science Applications
Spectroscopy
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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Pathophysiology of non alcoholic fatty liver disease. / Petta, Salvatore; Gastaldelli, Amalia; Rebelos, Eleni; Bugianesi, Elisabetta; Messa, Piergiorgio; Miele, Luca; Svegliati-Baroni, Gianluca; Valenti, Luca; Bonino, Ferruccio.

In: International Journal of Molecular Sciences, Vol. 17, No. 12, 2082, 11.12.2016.

Research output: Contribution to journal › Review article › peer-review

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