Fisiopatologia del mioclono

Translated title of the contribution: Pathophysiology of the myoclonus

Research output: Contribution to journalArticlepeer-review


Myoclonic jerks can occur in several neurological diseases at rest or during voluntary movements (intention and action myoclonus). The study of stimulus-sensitive or 'reflex' type of myoclonus has considerably advanced out understanding of its pathophysiology. By the combination of different stimulation and recording techniques (namely the jerk-locked averaging) different types of myclonus has been characterized, i.e. cortical and reticular reflex myoclonus. Recent results suggest that an inhibitory component of the myoclonus (sometimes seen in isolation: 'negative myoclonus') is due to the involvement of premotor inhibitory cortex. Myoclonic jerks are observed in several epileptic syndromes: a detailed neurophysiological study can significantly contribute to improve our understanding of the underlying pathophysiological mechanisms.

Translated title of the contributionPathophysiology of the myoclonus
Original languageItalian
Pages (from-to)451-455
Number of pages5
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number95-96
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Clinical Neurology


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