Patient-Derived Cancer Models

Maria Flavia Di Renzo; Simona Corso

doi:10.3390/cancers12123779

Patient-Derived Cancer Models

Maria Flavia Di Renzo, Simona Corso

Istituto Oncologico Candiolo

Research output: Contribution to journal › Article › peer-review

Abstract

For many decades, basic and preclinical cancer research has been based on the use of established, commercially available cell lines, originally derived from patients' samples but adapted to grow indefinitely in artificial culture conditions, and on xenograft models developed by injection of these cells in immunocompromised animals [...].

Original language	English
Journal	Cancers
Volume	12
Issue number	12
DOIs	https://doi.org/10.3390/cancers12123779
Publication status	Published - Dec 15 2020

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10.3390/cancers12123779

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title = "Patient-Derived Cancer Models",

abstract = "For many decades, basic and preclinical cancer research has been based on the use of established, commercially available cell lines, originally derived from patients' samples but adapted to grow indefinitely in artificial culture conditions, and on xenograft models developed by injection of these cells in immunocompromised animals [...].",

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