Patient-specific modeling of hemodynamics: Supporting surgical planning in a fontan circulation correction

Theodorus M.J. van Bakel, Kevin D. Lau, Jennifer Hirsch-Romano, Santi Trimarchi, Adam L. Dorfman, C. Alberto Figueroa

Research output: Contribution to journalArticle

Abstract

Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are being used to calculate patient-specific hemodynamics for a variety of applications, such as disease research, noninvasive diagnostics, medical device evaluation, and surgical planning. This paper provides a concise overview of the methods to perform patient-specific computational analyses using clinical data, followed by a case study where CFD-supported surgical planning is presented in a patient with Fontan circulation complicated by unilateral pulmonary arteriovenous malformations. In closing, the challenges for implementation and adoption of CFD modeling in clinical practice are discussed.

Original languageEnglish
Pages (from-to)145-155
Number of pages11
JournalJournal of Cardiovascular Translational Research
Volume11
Issue number2
DOIs
Publication statusPublished - Jan 1 2018

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Keywords

  • Computational fluid dynamics
  • Hemodynamics
  • Patient-specific modeling
  • Pulmonary arteriovenous malformations
  • Single ventricle
  • Surgical planning

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Pharmaceutical Science
  • Cardiology and Cardiovascular Medicine
  • Genetics(clinical)

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