Patients' evaluation of nocturnal hypoglycaemia with GlucoDay continuous glucose monitoring in paediatric patients

Franco Meschi, Riccardo Bonfanti, Andrea Rigamonti, Giulio Frontino, Roseila Battaglino, Matteo Viscardi, Alessandro Poscia, Giuseppe Chiumello

Research output: Contribution to journalArticlepeer-review

Abstract

A study was conducted to evaluate the accuracy of GlucoDay (A. Menarini Diagnostics) during 48 h of continuous glucose monitoring (CGMS) in type 1 diabetic adolescents and use this novel approach to assess otherwise ignored nocturnal hypoglycaemias, in relationship to intermediate-acting insulin administration timing. Twenty type 1 diabetic adolescents with poor metabolic control were selected from our out-patient department. Equal doses of intermediate insulin were administered at 19:00 and at 22:00 of the first and second night of the study, respectively. Correlation coefficient between GlucoDay and standard glucometer was 0.94; 98.3% of data fall in the A + B area of Error Grid Analysis and 1.7% in the D area. The mean error was 13.9% overall and 16.4% with blood glucose values (BGV) 75 mg/dl. The CGMS discovered nocturnal hypoglycaemia (NH) in 12/18 patients, but no severe hypoglycaemia. During the first night, 8 asymptomatic NH episodes were found with BGV

Original languageEnglish
Pages (from-to)295-300
Number of pages6
JournalActa Diabetologica
Volume47
Issue number4
DOIs
Publication statusPublished - Dec 2010

Keywords

  • CGMS
  • Hypoglycaemia
  • Insulin treatment
  • Nocturnal hypoglycaemia

ASJC Scopus subject areas

  • Endocrinology
  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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