Patients with migraine do not have MRI-visible cortical lesions

Research output: Contribution to journalArticle


Migraine patients with multiple brain white matter hyperintensities (WMHs) may represent a diagnostic challenge. Using double inversion recovery (DIR) imaging, we studied whether cortical lesions (CLs) could be seen in these patients. Approval of the institutional review boards and written informed consent were obtained from each participant. CLs and WM lesions were assessed on brain scans from 32 migraine patients with WMHs (17 patients with and 15 without aura), and in two control groups, consisting of 15 relapsing-remitting multiple sclerosis (RRMS) patients and 20 healthy controls, matched for age and gender. By definition, brain WM lesions were detected in all migraine and RRMS patients. The number and volume of WM lesions were lower in migraine versus RRMS patients (p

Original languageEnglish
Pages (from-to)2695-2698
Number of pages4
JournalJournal of Neurology
Issue number12
Publication statusPublished - Dec 2012


  • Cortical lesions
  • Migraine
  • Multiple sclerosis
  • White matter hyperintensities

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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