Pattern of cancer risk in persons with AIDS in Italy in the HAART era

L. Dal Maso, J. Polesel, D. Serraino, M. Lise, P. Piselli, F. Falcini, A. Russo, T. Intrieri, M. Vercelli, P. Zambon, G. Tagliabue, R. Zanetti, M. Federico, R. M. Limina, L. Mangone, V. De Lisi, F. Stracci, S. Ferretti, S. Piffer, M. BudroniA. Donato, A. Giacomin, F. Bellù, M. Fusco, A. Madeddu, S. Vitarelli, R. Tessandori, R. Tumino, B. Suligoi, S. Franceschi

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Abstract

A record-linkage study was carried out between the Italian AIDS Registry and 24 Italian cancer registries to compare cancer excess among persons with HIV/AIDS (PWHA) before and after the introduction of highly active antiretroviral therapy (HAART) in 1996. Standardised incidence ratios (SIR) were computed in 21951 AIDS cases aged 16-69 years reported between 1986 and 2005. Of 101 669 person-years available, 45 026 were after 1996. SIR for Kaposi sarcoma (KS) and non-Hodgkin lymphoma greatly decreased in 1997-2004 compared with 1986-1996, but high SIRs for KS persisted in the increasingly large fraction of PWHA who had an interval of

Original languageEnglish
Pages (from-to)840-847
Number of pages8
JournalBritish Journal of Cancer
Volume100
Issue number5
DOIs
Publication statusPublished - Mar 10 2009

Keywords

  • AIDS
  • Epidemiology
  • HAART
  • Hepatitis viruses
  • Human papillomavirus

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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