Pattern of frontal impairment in progressive supranuclear palsy and Parkinson's disease

R. Perri, V. Filippini, M. C. Silveri

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A group of 16 patients suffering from Progressive Supranuclear Palsy (PSP) and a group of 10 patients suffering from Parkinson's disease (PD) were submitted to a general neuropsychological examination and to a large set of frontal lobe tests in order to differentiate different degrees or different pattern of cognitive impairment. Both PSP and PD patients showed, compared to a control group, mild memory and visual perceptual deficit. A frontal lobe impairment was evident in both groups but with different characteristics: PSP patients presented & general impairment of frontal lobe tasks whereas PD patients showed a quite selective impairment in Wisconsin Card Sorting Test. This study confirms a relative preservation of general cognitive abilities in PD and PSP patients and the presence of a dysexecutive syndrome that may be qualitatively differentiated in the two illnesses.

Original languageEnglish
Pages (from-to)67
Number of pages1
JournalItalian Journal of Neurological Sciences
Issue number4
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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