Abstract
We describe two patients with lesions at different levels of the septo-hippocampal system. Both of them were selectively affected by anterograde amnesia, with a less severe retrograde amnesia. These data confirm that the integrity of the septo-hippocampal system is indispensable for the maintenance of normal memory and learning mechanisms and that the lesions along this fibre pathway, causing a functional and anatomic disconnection between the septal area (basal forebrain) and the medial temporal lobe structures, interfere with normal explicit memory functions.
Original language | English |
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Pages (from-to) | 377-384 |
Number of pages | 8 |
Journal | European Journal of Neurology |
Volume | 3 |
Issue number | 4 |
Publication status | Published - 1996 |
Keywords
- Amnesia
- Learning
- Septo-hippocampal disconnection
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)