Abstract
We describe two patients with lesions at different levels of the septo-hippocampal system. Both of them were selectively affected by anterograde amnesia, with a less severe retrograde amnesia. These data confirm that the integrity of the septo-hippocampal system is indispensable for the maintenance of normal memory and learning mechanisms and that the lesions along this fibre pathway, causing a functional and anatomic disconnection between the septal area (basal forebrain) and the medial temporal lobe structures, interfere with normal explicit memory functions.
| Original language | English |
|---|---|
| Pages (from-to) | 377-384 |
| Number of pages | 8 |
| Journal | European Journal of Neurology |
| Volume | 3 |
| Issue number | 4 |
| Publication status | Published - 1996 |
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Keywords
- Amnesia
- Learning
- Septo-hippocampal disconnection
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Almonti, S., Silveri, M. C., Gainotti, G., & Macchi, G. (1996). Pattern of memory impairment in two patients with septohippocampal disconnection. European Journal of Neurology, 3(4), 377-384.