Pattern visual evoked potentials and flash electroretinogram in clinically definite multiple sclerosis

F. Pierelli, G. Pozzessere, E. Stefano, M. Martelli, P. A. Pizzo, C. Moroeutti

Research output: Contribution to journalArticle


The authors have studied, by means of pattern visual evoked potential (VEP) and flash electroretinogram (ERG) recordings, a group of 15 patients affected by definite multiple sclerosis. All of the subjects examined presented a clinical history indicating involvement of the visual pathways; VEPs were altered in a high percentage of eyes examined (93.3%), while a lower percentage of abnormal ERGs was seen (20% of eyes examined). The only type of ERG alteration found consisted of a pathologic b wave voltage increase, observed mainly with red flash stimuli. This finding could be attributed to an involvement of centrifugal optic nerve fibers having inhibitory functions on retinal cells.

Original languageEnglish
Pages (from-to)324-329
Number of pages6
JournalEuropean Neurology
Issue number5
Publication statusPublished - 1985



  • Definite multiple sclerosis
  • Pattern visual evoked potentials
  • Retrobulbar neuritis
  • White and red flash electroretinogram

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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