Patterns and risk factors for locoregional failures after mastectomy for breast cancer: An International Breast Cancer Study Group Report

P. Karlsson; B. F. Cole; B. H. Chua; K. N. Price; J. Lindtner; J. P. Collins; A. Kovács; B. Thürlimann; D. Crivellari; M. Castiglione-Gertsch; J. F. Forbes; R. D. Gelber; A. Goldhirsch; G. Gruber

doi:10.1093/annonc/mds118

Patterns and risk factors for locoregional failures after mastectomy for breast cancer: An International Breast Cancer Study Group Report

P. Karlsson, B. F. Cole, B. H. Chua, K. N. Price, J. Lindtner, J. P. Collins, A. Kovács, B. Thürlimann, D. Crivellari, M. Castiglione-Gertsch, J. F. Forbes, R. D. Gelber, A. Goldhirsch, G. Gruber

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Rates and risk factors of local, axillary and supraclavicular recurrences can guide patient selection and target for postmastectomy radiotherapy (PMRT). Patients and methods: Local, axillary and supraclavicular recurrences were evaluated in 8106 patients enrolled in 13 randomized trials. Patients received chemotherapy and/or endocrine therapy and mastectomy without radiotherapy. Median follow-up was 15.2 years. Results: Ten-year cumulative incidence for chest wall recurrence of >15% was seen in patients aged 10%: ≥4 positive nodes (10.2%); for axillary failures of >5%: aged 15% were age

Original language	English
Article number	mds118
Pages (from-to)	2852-2858
Number of pages	7
Journal	Annals of Oncology
Volume	23
Issue number	11
DOIs	https://doi.org/10.1093/annonc/mds118
Publication status	Published - Nov 2012

Keywords

Adjuvant treatment
Breast cancer
Locoregional recurrence
Postmastectomy radiotherapy

ASJC Scopus subject areas

Oncology
Hematology

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Karlsson, P., Cole, B. F., Chua, B. H., Price, K. N., Lindtner, J., Collins, J. P., Kovács, A., Thürlimann, B., Crivellari, D., Castiglione-Gertsch, M., Forbes, J. F., Gelber, R. D., Goldhirsch, A., & Gruber, G. (2012). Patterns and risk factors for locoregional failures after mastectomy for breast cancer: An International Breast Cancer Study Group Report. Annals of Oncology, 23(11), 2852-2858. [mds118]. https://doi.org/10.1093/annonc/mds118

Patterns and risk factors for locoregional failures after mastectomy for breast cancer : An International Breast Cancer Study Group Report. / Karlsson, P.; Cole, B. F.; Chua, B. H.; Price, K. N.; Lindtner, J.; Collins, J. P.; Kovács, A.; Thürlimann, B.; Crivellari, D.; Castiglione-Gertsch, M.; Forbes, J. F.; Gelber, R. D.; Goldhirsch, A.; Gruber, G.

In: Annals of Oncology, Vol. 23, No. 11, mds118, 11.2012, p. 2852-2858.

Research output: Contribution to journal › Article › peer-review

Karlsson, P, Cole, BF, Chua, BH, Price, KN, Lindtner, J, Collins, JP, Kovács, A, Thürlimann, B, Crivellari, D, Castiglione-Gertsch, M, Forbes, JF, Gelber, RD, Goldhirsch, A & Gruber, G 2012, 'Patterns and risk factors for locoregional failures after mastectomy for breast cancer: An International Breast Cancer Study Group Report', Annals of Oncology, vol. 23, no. 11, mds118, pp. 2852-2858. https://doi.org/10.1093/annonc/mds118

Karlsson, P. ; Cole, B. F. ; Chua, B. H. ; Price, K. N. ; Lindtner, J. ; Collins, J. P. ; Kovács, A. ; Thürlimann, B. ; Crivellari, D. ; Castiglione-Gertsch, M. ; Forbes, J. F. ; Gelber, R. D. ; Goldhirsch, A. ; Gruber, G. / Patterns and risk factors for locoregional failures after mastectomy for breast cancer : An International Breast Cancer Study Group Report. In: Annals of Oncology. 2012 ; Vol. 23, No. 11. pp. 2852-2858.

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abstract = "Background: Rates and risk factors of local, axillary and supraclavicular recurrences can guide patient selection and target for postmastectomy radiotherapy (PMRT). Patients and methods: Local, axillary and supraclavicular recurrences were evaluated in 8106 patients enrolled in 13 randomized trials. Patients received chemotherapy and/or endocrine therapy and mastectomy without radiotherapy. Median follow-up was 15.2 years. Results: Ten-year cumulative incidence for chest wall recurrence of >15% was seen in patients aged 10%: ≥4 positive nodes (10.2%); for axillary failures of >5%: aged 15% were age ",

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