Patterns and risk factors for locoregional failures after mastectomy for breast cancer: An International Breast Cancer Study Group Report

P. Karlsson, B. F. Cole, B. H. Chua, K. N. Price, J. Lindtner, J. P. Collins, A. Kovács, B. Thürlimann, D. Crivellari, M. Castiglione-Gertsch, J. F. Forbes, R. D. Gelber, A. Goldhirsch, G. Gruber

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Rates and risk factors of local, axillary and supraclavicular recurrences can guide patient selection and target for postmastectomy radiotherapy (PMRT). Patients and methods: Local, axillary and supraclavicular recurrences were evaluated in 8106 patients enrolled in 13 randomized trials. Patients received chemotherapy and/or endocrine therapy and mastectomy without radiotherapy. Median follow-up was 15.2 years. Results: Ten-year cumulative incidence for chest wall recurrence of >15% was seen in patients aged 10%: ≥4 positive nodes (10.2%); for axillary failures of >5%: aged 15% were age

Original languageEnglish
Article numbermds118
Pages (from-to)2852-2858
Number of pages7
JournalAnnals of Oncology
Volume23
Issue number11
DOIs
Publication statusPublished - Nov 2012

Keywords

  • Adjuvant treatment
  • Breast cancer
  • Locoregional recurrence
  • Postmastectomy radiotherapy

ASJC Scopus subject areas

  • Oncology
  • Hematology

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