TY - JOUR
T1 - Patterns of antibodies to hepatitis C virus and hepatitis C virus replication in children with chronic non-A, non-B hepatitis
AU - Bortolotti, F.
AU - Vajro, P.
AU - Barbera, C.
AU - Crivellaro, C.
AU - Zancan, L.
AU - Giacchino, R.
AU - Nebbia, G.
AU - Lepore, L.
AU - Barbierato, E.
AU - De Moliner, L.
AU - Cavalletto, D.
AU - Alberti, A.
PY - 1994
Y1 - 1994
N2 - Antibodies to hepatitis C virus (HCV), investigated by second- and third-generation assays, were detected in 74% of 43 children with chronic non-A, non-B hepatitis. The polymerase chain reaction identified HCV ribonucleic acid in 26 (93%) of 28 seropositive and in 1 of 10 seronegative cases. Intermittent HCV ribonucleic acid positivity, suggesting low and fluctuating viremia, was frequent in younger patients. (J PEDIATR 1994;125:916-8).
AB - Antibodies to hepatitis C virus (HCV), investigated by second- and third-generation assays, were detected in 74% of 43 children with chronic non-A, non-B hepatitis. The polymerase chain reaction identified HCV ribonucleic acid in 26 (93%) of 28 seropositive and in 1 of 10 seronegative cases. Intermittent HCV ribonucleic acid positivity, suggesting low and fluctuating viremia, was frequent in younger patients. (J PEDIATR 1994;125:916-8).
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U2 - 10.1016/S0022-3476(05)82009-8
DO - 10.1016/S0022-3476(05)82009-8
M3 - Article
C2 - 7527849
AN - SCOPUS:0027945425
VL - 125
SP - 916
EP - 918
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 6 PART 1
ER -