Patterns of antibodies to hepatitis C virus and hepatitis C virus replication in children with chronic non-A, non-B hepatitis

F. Bortolotti, P. Vajro, C. Barbera, C. Crivellaro, L. Zancan, R. Giacchino, G. Nebbia, L. Lepore, E. Barbierato, L. De Moliner, D. Cavalletto, A. Alberti

Research output: Contribution to journalArticlepeer-review

Abstract

Antibodies to hepatitis C virus (HCV), investigated by second- and third-generation assays, were detected in 74% of 43 children with chronic non-A, non-B hepatitis. The polymerase chain reaction identified HCV ribonucleic acid in 26 (93%) of 28 seropositive and in 1 of 10 seronegative cases. Intermittent HCV ribonucleic acid positivity, suggesting low and fluctuating viremia, was frequent in younger patients. (J PEDIATR 1994;125:916-8).

Original languageEnglish
Pages (from-to)916-918
Number of pages3
JournalJournal of Pediatrics
Volume125
Issue number6 PART 1
DOIs
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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