TY - JOUR
T1 - Patterns of care and cost profiles of women with breast cancer in Italy
T2 - EPICOST study based on real world data
AU - Francisci, Silvia
AU - Guzzinati, Stefano
AU - Capodaglio, Giulia
AU - Pierannunzio, Daniela
AU - Mallone, Sandra
AU - Tavilla, Andrea
AU - Lopez, Tania
AU - Busco, Susanna
AU - Mazzucco, Walter
AU - Angiolini, Catia
AU - Zorzi, Manuel
AU - Serraino, Diego
AU - Barchielli, Alessandro
AU - Fusco, Mario
AU - Stracci, Fabrizio
AU - Bianconi, Fortunato
AU - Rugge, Massimo
AU - Iacovacci, Silvia
AU - Russo, Antonio Giampiero
AU - Cusimano, Rosanna
AU - Gigli, Anna
N1 - Funding Information:
The study was supported by the National Centre for Disease Prevention and Control of the Italian Ministry of Health, Grant 2014.
Publisher Copyright:
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Objectives: To estimate total direct health care costs associated to diagnosis and treatment of women with breast cancer in Italy, and to investigate their distribution by service type according to the disease pathway and patient characteristics. Methods: Data on patients provided by population-based Cancer Registries are linked at individual level with data on health-care services and corresponding claims from administrative databases. A combination of cross-sectional approach and a threephase of care decomposition model with initial, continuing and final phases-of-care defined according to time occurred since diagnosis and disease outcome is adopted. Direct estimation of cancer-related costs is obtained. Results: Study cohort included 49,272 patients, 15.2% were in the initial phase absorbing 42% of resources, 79.7% in the continuing phase absorbing 44% of resources and 5.1% in the final phase absorbing 14% of resources. Hospitalization was the most important cost driver, accounting for over 55% of the total costs. Conclusions: This paper represents the first attempt in Italy to estimate the economic burden of cancer at population level taking into account the entire disease pathway and using multiple current health care databases. The evidence produced by the study can be used to better plan resources allocation. The model proposed is replicable to countries with individual health care information on services and claims.
AB - Objectives: To estimate total direct health care costs associated to diagnosis and treatment of women with breast cancer in Italy, and to investigate their distribution by service type according to the disease pathway and patient characteristics. Methods: Data on patients provided by population-based Cancer Registries are linked at individual level with data on health-care services and corresponding claims from administrative databases. A combination of cross-sectional approach and a threephase of care decomposition model with initial, continuing and final phases-of-care defined according to time occurred since diagnosis and disease outcome is adopted. Direct estimation of cancer-related costs is obtained. Results: Study cohort included 49,272 patients, 15.2% were in the initial phase absorbing 42% of resources, 79.7% in the continuing phase absorbing 44% of resources and 5.1% in the final phase absorbing 14% of resources. Hospitalization was the most important cost driver, accounting for over 55% of the total costs. Conclusions: This paper represents the first attempt in Italy to estimate the economic burden of cancer at population level taking into account the entire disease pathway and using multiple current health care databases. The evidence produced by the study can be used to better plan resources allocation. The model proposed is replicable to countries with individual health care information on services and claims.
KW - Administrative data
KW - Breast cancer
KW - Cost analysis
KW - Health care utilization
KW - Real world data
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U2 - 10.1007/s10198-020-01190-z
DO - 10.1007/s10198-020-01190-z
M3 - Article
VL - 21
SP - 1003
EP - 1013
JO - European Journal of Health Economics
JF - European Journal of Health Economics
SN - 1618-7598
IS - 7
ER -