Patterns of cerebrovascular reactivity in patients with carotid artery occlusion and severe contralateral stenosis

Maria Matteis, Fabrizio Vernieri, Carlo Caltagirone, Elio Troisi, Paolo M. Rossini, Mauro Silvestrini

Research output: Contribution to journalArticle

Abstract

There is evidence suggesting that among other factors, an alteration in cerebral hemodynamics plays a relevant role in the occurrence of strokes in patients with carotid disease. The purpose of this study was to investigate patterns of cerebrovascular reactivity in patients with internal carotid occlusion and severe contralateral carotid stenosis and their relationship with symptomatology. Using transcranial Doppler ultrasound, cerebrovascular reactivity to hypercapnia in middle cerebral arteries was evaluated with the breath-holding index (BHI) in 42 patients with internal carotid occlusion and severe contralateral carotid stenosis and in 40 control subjects. A significant decrease of BHI on the occluded side was observed in symptomatic patients with respect to asymptomatic ones (0.12±0.1 vs. 0.75±0.4, P

Original languageEnglish
Pages (from-to)47-51
Number of pages5
JournalJournal of the Neurological Sciences
Volume168
Issue number1
DOIs
Publication statusPublished - Sep 15 1999

Keywords

  • Carotid artery occlusion
  • Cerebral blood flow
  • Hemodynamics
  • Ultrasonics

ASJC Scopus subject areas

  • Ageing
  • Clinical Neurology
  • Surgery
  • Developmental Neuroscience
  • Neurology
  • Neuroscience(all)

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