Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates

Philipp Oster, Alessandra Zanchi, Stefania Cresti, Maria Lattanzi, Francesca Montagnani, Carla Cellesi, Gian Maria Rossolini

Research output: Contribution to journalArticle

Abstract

Erythromycin resistance rates were found to be increased, from 7.1 in 1993 to 32.8% in 1997, among community-acquired Streptococcus pneumoniae isolates from the Siena area of central Italy. Most of the erythromycin- resistant isolates carried ermAM determinants and were also resistant to josamycin and clindamycin, whereas a minority (5.8%) carried mefA determinants and remained susceptible to the latter drugs.

Original languageEnglish
Pages (from-to)2510-2512
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume43
Issue number10
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Pharmacology (medical)

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