TY - JOUR
T1 - Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part II
T2 - Offline and online plan adaption for interfractional changes
AU - Bertholet, Jenny
AU - Anastasi, Gail
AU - Noble, David
AU - Bel, Arjan
AU - van Leeuwen, Ruud
AU - Roggen, Toon
AU - Duchateau, Michael
AU - Pilskog, Sara
AU - Garibaldi, Cristina
AU - Tilly, Nina
AU - García-Mollá, Rafael
AU - Bonaque, Jorge
AU - Oelfke, Uwe
AU - Aznar, Marianne C.
AU - Heijmen, Ben
N1 - Funding Information:
Gail Anastasi acknowledges funding from the UK National Institute for Health Research (NIHR), (Doctoral Research Fellowship). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.
Funding Information:
Jenny Bertholet acknowledges funding from the Stand Up to Cancer campaign for Cancer Research UK (C33589/A19727 and C33589/A19908) and the CRUK ART-NET Network Accelerator Award (A21993) as well as NHS funding to the NIHR Biomedical Research Centre at The Royal Marsden and The Institute of Cancer Research.Marianne Aznar acknowledges support from Cancer Research UK [grant no C8225/A21133] and of the NIHR Manchester Biomedical Research Centre.
Publisher Copyright:
© 2020 The Authors
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2020/12
Y1 - 2020/12
N2 - Purpose: The POP-ART RT study aims to determine to what extent and how intrafractional real-time respiratory motion management (RRMM), and plan adaptation for interfractional anatomical changes (ART) are used in clinical practice and to understand barriers to implementation. Here we report on part II: ART using more than one plan per target per treatment course. Materials and methods: A questionnaire on the current practice of ART, wishes for expansion or implementation, and barriers to implementation was distributed worldwide. Four types of ART were discriminated: daily online replanning, online plan library, protocolled offline replanning (all three based on a protocol), and ad-hoc offline replanning. Results: The questionnaire was completed by 177 centres from 40 countries. ART was used by 61% of respondents (31% with protocol) for a median (range) of 3 (1–8) tumour sites. CBCT/MVCT was the main imaging modality except for online daily replanning (11 users) where 10 users used MR. Two thirds of respondents wished to implement ART for a new tumour site; 40% of these had plans to do it in the next 2 years. Human/material resources and technical limitations were the main barriers to further use and implementation. Conclusions: ART was used for a broad range of tumour sites, mainly with ad-hoc offline replanning and for a median of 3 tumour sites. There was a large interest in implementing ART for more tumour sites, mainly limited by human/material resources and technical limitations. Daily online replanning was primarily performed on MR-linacs.
AB - Purpose: The POP-ART RT study aims to determine to what extent and how intrafractional real-time respiratory motion management (RRMM), and plan adaptation for interfractional anatomical changes (ART) are used in clinical practice and to understand barriers to implementation. Here we report on part II: ART using more than one plan per target per treatment course. Materials and methods: A questionnaire on the current practice of ART, wishes for expansion or implementation, and barriers to implementation was distributed worldwide. Four types of ART were discriminated: daily online replanning, online plan library, protocolled offline replanning (all three based on a protocol), and ad-hoc offline replanning. Results: The questionnaire was completed by 177 centres from 40 countries. ART was used by 61% of respondents (31% with protocol) for a median (range) of 3 (1–8) tumour sites. CBCT/MVCT was the main imaging modality except for online daily replanning (11 users) where 10 users used MR. Two thirds of respondents wished to implement ART for a new tumour site; 40% of these had plans to do it in the next 2 years. Human/material resources and technical limitations were the main barriers to further use and implementation. Conclusions: ART was used for a broad range of tumour sites, mainly with ad-hoc offline replanning and for a median of 3 tumour sites. There was a large interest in implementing ART for more tumour sites, mainly limited by human/material resources and technical limitations. Daily online replanning was primarily performed on MR-linacs.
KW - Adaptive radiotherapy
KW - Image-guided radiotherapy (IGRT)
KW - Interfractional motion
KW - MR-guided radiotherapy
KW - Plan library
KW - Plan of the day
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U2 - 10.1016/j.radonc.2020.06.017
DO - 10.1016/j.radonc.2020.06.017
M3 - Article
C2 - 32579998
AN - SCOPUS:85087373619
VL - 153
SP - 88
EP - 96
JO - Radiotherapy and Oncology
JF - Radiotherapy and Oncology
SN - 0167-8140
ER -