@article{bd017126775d4224a40860b0aa938472,
title = "Patterns of recurrence and survival probability after second recurrence of retroperitoneal sarcoma: A study from TARPSWG",
abstract = "Background: In this series from the Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG), the authors examined longitudinal outcomes of patients with a second recurrence of retroperitoneal sarcoma (RPS) after complete resection of a first local recurrence (LR). Methods: Data from patients undergoing resection of a first LR from January 2002 to December 2011were collected from 22 sarcoma centers. The primary outcome was overall survival (OS) after second recurrence. Results: Second recurrences occurred in 400 of 567 patients (70.5%) after an R0/R1 resection of a first locally recurrent RPS. Patterns of disease recurrence were LR in 323 patients (80.75%), distant metastases (DM) in 55 patients (13.75%), and both LR and DM in 22 patients (5.5%). The main subtype among the LR group was liposarcoma (77%), whereas DM mainly were leiomyosarcomas (43.6%). In patients with a second LR only, a total of 200 patients underwent re-resection (61.9%). The 5-year OS rate varied significantly based on the pattern of failure (P ",
keywords = "leiomyosarcoma, liposarcoma, recurrence, retroperitoneal sarcoma, adult, aged, Article, cancer chemotherapy, cancer classification, cancer radiotherapy, cancer recurrence, cancer survival, controlled study, dedifferentiated liposarcoma, disease free survival, distant metastasis, female, follow up, histopathology, human, human tissue, major clinical study, male, malignant fibrous histiocytoma cell line, middle aged, overall survival, peripheral nerve tumor, priority journal, probability, solitary fibrous tumor, survival rate, well differentiated liposarcoma",
author = "{van Houdt}, W.J. and M. Fiore and F. Barretta and P. Rutkowski and J.-Y. Blay and G. Lahat and D. Strauss and R.J. Gonzalez and N. Ahuja and G. Grignani and V. Quagliuolo and E. Stoeckle and {De Paoli}, A. and Y. Schrage and K. Cardona and E. Pennacchioli and V.G. Pillarisetty and C. Nessim and C.J. Swallow and S.P. Bagaria and R. Canter and J.T. Mullen and D. Callegaro and M. Fairweather and R. Miceli and C.P. Raut and A. Gronchi and R.A. Gladdy",
note = "Cited By :1 Export Date: 18 February 2021 CODEN: CANCA Correspondence Address: Gladdy, R.A.; Division of General Surgery, Canada; email: rebecca.gladdy@sinaihealth.ca References: Brennan, M.F., Antonescu, C.R., Moraco, N., Singer, S., Lessons learned from the study of 10,000 patients with soft tissue sarcoma (2014) Ann Surg, 260, pp. 416-421. , discussion 421-422; Management of primary retroperitoneal sarcoma (RPS) in the adult: a consensus approach from the Trans-Atlantic RPS Working Group (2015) Ann Surg Oncol, 22, pp. 256-263; Tan, M.C., Brennan, M.F., Kuk, D., Histology-based classification predicts pattern of recurrence and improves risk stratification in primary retroperitoneal sarcoma (2016) Ann Surg, 263, pp. 593-600; Gronchi, A., Strauss, D.C., Miceli, R., Variability in patterns of recurrence after resection of primary retroperitoneal sarcoma (RPS): a report on 1007 patients from the multi-institutional collaborative RPS Working Group (2016) Ann Surg, 263, pp. 1002-1009; van Houdt, W.J., Zaidi, S., Messiou, C., Thway, K., Strauss, D.C., Jones, R.L., Treatment of retroperitoneal sarcoma: current standards and new developments (2017) Curr Opin Oncol, 29, pp. 260-267; Linehan, D.C., Lewis, J.J., Leung, D., Brennan, M.F., Influence of biologic factors and anatomic site in completely resected liposarcoma (2000) J Clin Oncol, 18, pp. 1637-1643; Stojadinovic, A., Yeh, A., Brennan, M.F., Completely resected recurrent soft tissue sarcoma: primary anatomic site governs outcomes (2002) J Am Coll Surg, 194, pp. 436-447; Park, J.O., Qin, L.X., Prete, F.P., Antonescu, C., Brennan, M.F., Singer, S., Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule (2009) Ann Surg, 250, pp. 977-982; Gronchi, A., Lo Vullo, S., Fiore, M., Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients (2009) J Clin Oncol, 27, pp. 24-30; Bonvalot, S., Miceli, R., Berselli, M., Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control (2010) Ann Surg Oncol, 17, pp. 1507-1514; Gronchi, A., Miceli, R., Colombo, C., Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas (2012) Ann Oncol, 23, pp. 1067-1073; Management of recurrent retroperitoneal sarcoma (RPS) in the adult: a consensus approach from the Trans-Atlantic RPS Working Group (2016) Ann Surg Oncol, 23, pp. 3531-3540; Management of metastatic retroperitoneal sarcoma: a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) (2018) Ann Oncol, 29, pp. 857-871; MacNeill, A.J., Gronchi, A., Miceli, R., Postoperative morbidity after radical resection of primary retroperitoneal sarcoma: a report from the Transatlantic RPS Working Group (2018) Ann Surg, 267, pp. 959-964; Raut, C.P., Callegaro, D., Miceli, R., Predicting survival in patients undergoing resection for locally recurrent retroperitoneal sarcoma: a study and novel nomogram from TARPSWG (2019) Clin Cancer Res, 25, pp. 2664-2671; MacNeill, A.J., Miceli, R., Strauss, D.C., Post-relapse outcomes after primary extended resection of retroperitoneal sarcoma: a report from the Trans-Atlantic RPS Working Group (2017) Cancer, 123, pp. 1971-1978; Lewis, J.J., Leung, D., Woodruff, J.M., Brennan, M.F., Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution (1998) Ann Surg, 228, pp. 355-365; van Houdt, W.J., Raut, C.P., Bonvalot, S., Swallow, C.J., Haas, R., Gronchi, A., New research strategies in retroperitoneal sarcoma. The case of TARPSWG, STRASS and RESAR: making progress through collaboration (2019) Curr Opin Oncol, 31, pp. 310-316",
year = "2020",
doi = "10.1002/cncr.33139",
language = "English",
volume = "126",
pages = "4917--4925",
journal = "Cancer",
issn = "0008-543X",
publisher = "John Wiley and Sons Inc.",
number = "22",
}