Patterns of restenosis after drug-eluting stent implantation: Insights from a contemporary and comparative analysis of sirolimus- and paclitaxel-eluting stents

Simon J. Corbett, John Cosgrave, Gloria Melzi, Rade Babic, Giuseppe G L Biondi-Zoccai, Cosmo Godino, Nuccia Morici, Flavio Airoldi, Iassen Michev, Matteo Montorfano, Giuseppe M. Sangiorgi, Erminio Bonizzoni, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To evaluate patterns of restenosis following implantation of sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) in comparable unselected lesions. Methods and results: We have identified all episodes of restenosis after SES or PES implantation in our institutions between March 2003 and March 2005. Restenosis pattern was classified as focal, diffuse, proliferative, or occlusive. The position of focal restenosis was also categorized as proximal, in-stent, distal, or multi-focal. We have characterized 150 and 149 restenotic lesions in SES and PES groups, respectively. The incidence of diffuse and occlusive restenosis was significantly higher in PES than in SES (47.6 vs. 27.0%, P

Original languageEnglish
Pages (from-to)2330-2337
Number of pages8
JournalEuropean Heart Journal
Volume27
Issue number19
DOIs
Publication statusPublished - Oct 2006

Keywords

  • Paclitaxel
  • Restenosis
  • Sirolimus
  • Stent

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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