PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers: From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering

R. De Santis; A. Gloria; T. Russo; U. D'Amora; V. D'Antò; F. Bollino; M. Catauro; F. Mollica; S. Rengo; L. Ambrosio

doi:10.1063/1.4738387

PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers: From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering

R. De Santis, A. Gloria, T. Russo, U. D'Amora, V. D'Antò, F. Bollino, M. Catauro, F. Mollica, S. Rengo, L. Ambrosio

Ospedale Pediatrico Bambino Gesu

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

As reported in the literature, scaffolds for soft and hard tissue regeneration should satisfy several requirements. In the present work, the potential of 3D fiber deposition technique to design morphologically controlled scaffolds consisting of poly(ε-caprolactone) reinforced with sol-gel synthesized organic-inorganic hybrid fillers was demonstrated, also benefiting from a basic study carried out on 2D composite substrates. Finite element analysis, biological and mechanical tests were properly performed to assess the effects of the inclusion of the hybrid fillers on the performances of 2D substrates and 3D structures.

Original language	English
Title of host publication	AIP Conference Proceedings
Pages	26-29
Number of pages	4
Volume	1459
Edition	1
DOIs	https://doi.org/10.1063/1.4738387
Publication status	Published - 2012
Event	6th International Conference on Times of Polymers (TOP) and Composites - Ischia, Italy Duration: Jun 10 2012 → Jun 14 2012

Other

Other	6th International Conference on Times of Polymers (TOP) and Composites
Country	Italy
City	Ischia
Period	6/10/12 → 6/14/12

Keywords

Alamar Blue™ assay
Composite scaffolds
Finite element analysis
Mechanical properties
Organic-inorganic hybrid
Poly(e-caprolactone)
Tissue engineering

ASJC Scopus subject areas

Physics and Astronomy(all)

Access to Document

10.1063/1.4738387

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Santis, R. D., Gloria, A., Russo, T., D'Amora, U., D'Antò, V., Bollino, F., Catauro, M., Mollica, F., Rengo, S., & Ambrosio, L. (2012). PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers: From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering. In AIP Conference Proceedings (1 ed., Vol. 1459, pp. 26-29) https://doi.org/10.1063/1.4738387

PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers : From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering. / Santis, R. De; Gloria, A.; Russo, T.; D'Amora, U.; D'Antò, V.; Bollino, F.; Catauro, M.; Mollica, F.; Rengo, S.; Ambrosio, L.

AIP Conference Proceedings. Vol. 1459 1. ed. 2012. p. 26-29.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Santis, RD, Gloria, A, Russo, T, D'Amora, U, D'Antò, V, Bollino, F, Catauro, M, Mollica, F, Rengo, S & Ambrosio, L 2012, PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers: From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering. in AIP Conference Proceedings. 1 edn, vol. 1459, pp. 26-29, 6th International Conference on Times of Polymers (TOP) and Composites, Ischia, Italy, 6/10/12. https://doi.org/10.1063/1.4738387

Santis, R. De ; Gloria, A. ; Russo, T. ; D'Amora, U. ; D'Antò, V. ; Bollino, F. ; Catauro, M. ; Mollica, F. ; Rengo, S. ; Ambrosio, L. / PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers : From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering. AIP Conference Proceedings. Vol. 1459 1. ed. 2012. pp. 26-29

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