Abstract
As reported in the literature, scaffolds for soft and hard tissue regeneration should satisfy several requirements. In the present work, the potential of 3D fiber deposition technique to design morphologically controlled scaffolds consisting of poly(ε-caprolactone) reinforced with sol-gel synthesized organic-inorganic hybrid fillers was demonstrated, also benefiting from a basic study carried out on 2D composite substrates. Finite element analysis, biological and mechanical tests were properly performed to assess the effects of the inclusion of the hybrid fillers on the performances of 2D substrates and 3D structures.
| Original language | English |
|---|---|
| Title of host publication | AIP Conference Proceedings |
| Pages | 26-29 |
| Number of pages | 4 |
| Volume | 1459 |
| Edition | 1 |
| DOIs | |
| Publication status | Published - 2012 |
| Event | 6th International Conference on Times of Polymers (TOP) and Composites - Ischia, Italy Duration: Jun 10 2012 → Jun 14 2012 |
Other
| Other | 6th International Conference on Times of Polymers (TOP) and Composites |
|---|---|
| Country | Italy |
| City | Ischia |
| Period | 6/10/12 → 6/14/12 |
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Keywords
- Alamar Blue™ assay
- Composite scaffolds
- Finite element analysis
- Mechanical properties
- Organic-inorganic hybrid
- Poly(e-caprolactone)
- Tissue engineering
ASJC Scopus subject areas
- Physics and Astronomy(all)
Cite this
PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers : From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering. / Santis, R. De; Gloria, A.; Russo, T.; D'Amora, U.; D'Antò, V.; Bollino, F.; Catauro, M.; Mollica, F.; Rengo, S.; Ambrosio, L.
AIP Conference Proceedings. Vol. 1459 1. ed. 2012. p. 26-29.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - PCL loaded with sol-gel synthesized organic-inorganic hybrid fillers
T2 - From the analysis of 2D substrates to the design of 3D rapid prototyped composite scaffolds for tissue engineering
AU - Santis, R. De
AU - Gloria, A.
AU - Russo, T.
AU - D'Amora, U.
AU - D'Antò, V.
AU - Bollino, F.
AU - Catauro, M.
AU - Mollica, F.
AU - Rengo, S.
AU - Ambrosio, L.
PY - 2012
Y1 - 2012
N2 - As reported in the literature, scaffolds for soft and hard tissue regeneration should satisfy several requirements. In the present work, the potential of 3D fiber deposition technique to design morphologically controlled scaffolds consisting of poly(ε-caprolactone) reinforced with sol-gel synthesized organic-inorganic hybrid fillers was demonstrated, also benefiting from a basic study carried out on 2D composite substrates. Finite element analysis, biological and mechanical tests were properly performed to assess the effects of the inclusion of the hybrid fillers on the performances of 2D substrates and 3D structures.
AB - As reported in the literature, scaffolds for soft and hard tissue regeneration should satisfy several requirements. In the present work, the potential of 3D fiber deposition technique to design morphologically controlled scaffolds consisting of poly(ε-caprolactone) reinforced with sol-gel synthesized organic-inorganic hybrid fillers was demonstrated, also benefiting from a basic study carried out on 2D composite substrates. Finite element analysis, biological and mechanical tests were properly performed to assess the effects of the inclusion of the hybrid fillers on the performances of 2D substrates and 3D structures.
KW - Alamar Blue™ assay
KW - Composite scaffolds
KW - Finite element analysis
KW - Mechanical properties
KW - Organic-inorganic hybrid
KW - Poly(e-caprolactone)
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84872396320&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872396320&partnerID=8YFLogxK
U2 - 10.1063/1.4738387
DO - 10.1063/1.4738387
M3 - Conference contribution
AN - SCOPUS:84872396320
SN - 9780735410626
VL - 1459
SP - 26
EP - 29
BT - AIP Conference Proceedings
ER -