Pediatric atypical spitzoid neoplasms: A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors

Gerardo Ferrara, Iris Zalaudek, Imma Savarese, Massimiliano Scalvenzi, Giuseppe Argenziano

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The diagnosis of pediatric atypical Spitz nevus/tumors (pASNT) is an emerging challenge in clinical dermatology and dermatopathology. Objective and Methods: We review the main clinicopathologic issues raised by pASNT and describe 2 examples of different clinicopathologic subsets of lesions. Results: While Spitz/Reed nevi are commonly small- to medium-sized, tan to black plaques, pASNT are large and nodular, either 'red' (dotted and/or polymorphous vascular pattern on dermoscopy; spindle and/or epithelioid tumors on histopathology: Spitz tumors, sensu strictiori) or 'blue' (homogeneous blue color on dermoscopy; intimate admixture of epithelioid cells and heavily pigmented dendritic cells on histopathology: Blitz tumors or pigmented epithelioid melanocytomas). Conclusions: Different clinicopathologic settings of pASNT probably exist. Dermoscopy can aid in their recognition and classification.

Original languageEnglish
Pages (from-to)306-310
Number of pages5
JournalDermatology
Volume220
Issue number4
DOIs
Publication statusPublished - 2010

Keywords

  • Atypical Spitz nevus/tumor
  • Dermoscopy
  • Histopathology
  • Spitz nevus

ASJC Scopus subject areas

  • Dermatology
  • Medicine(all)

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