Pediatric atypical spitzoid neoplasms: A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors

Gerardo Ferrara, Iris Zalaudek, Imma Savarese, Massimiliano Scalvenzi, Giuseppe Argenziano

Research output: Contribution to journalArticle

Abstract

Background: The diagnosis of pediatric atypical Spitz nevus/tumors (pASNT) is an emerging challenge in clinical dermatology and dermatopathology. Objective and Methods: We review the main clinicopathologic issues raised by pASNT and describe 2 examples of different clinicopathologic subsets of lesions. Results: While Spitz/Reed nevi are commonly small- to medium-sized, tan to black plaques, pASNT are large and nodular, either 'red' (dotted and/or polymorphous vascular pattern on dermoscopy; spindle and/or epithelioid tumors on histopathology: Spitz tumors, sensu strictiori) or 'blue' (homogeneous blue color on dermoscopy; intimate admixture of epithelioid cells and heavily pigmented dendritic cells on histopathology: Blitz tumors or pigmented epithelioid melanocytomas). Conclusions: Different clinicopathologic settings of pASNT probably exist. Dermoscopy can aid in their recognition and classification.

Original languageEnglish
Pages (from-to)306-310
Number of pages5
JournalDermatology
Volume220
Issue number4
DOIs
Publication statusPublished - 2010

Fingerprint

Epithelioid and Spindle Cell Nevus
Pediatrics
Dermoscopy
Neoplasms
Epithelioid Cells
Dermatology
Dendritic Cells
Blood Vessels
Color

Keywords

  • Atypical Spitz nevus/tumor
  • Dermoscopy
  • Histopathology
  • Spitz nevus

ASJC Scopus subject areas

  • Dermatology
  • Medicine(all)

Cite this

Pediatric atypical spitzoid neoplasms : A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors. / Ferrara, Gerardo; Zalaudek, Iris; Savarese, Imma; Scalvenzi, Massimiliano; Argenziano, Giuseppe.

In: Dermatology, Vol. 220, No. 4, 2010, p. 306-310.

Research output: Contribution to journalArticle

Ferrara, G, Zalaudek, I, Savarese, I, Scalvenzi, M & Argenziano, G 2010, 'Pediatric atypical spitzoid neoplasms: A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors', Dermatology, vol. 220, no. 4, pp. 306-310. https://doi.org/10.1159/000300093
Ferrara, Gerardo ; Zalaudek, Iris ; Savarese, Imma ; Scalvenzi, Massimiliano ; Argenziano, Giuseppe. / Pediatric atypical spitzoid neoplasms : A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors. In: Dermatology. 2010 ; Vol. 220, No. 4. pp. 306-310.
@article{65466252d9654caf930a27136514ebbb,
title = "Pediatric atypical spitzoid neoplasms: A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors",
abstract = "Background: The diagnosis of pediatric atypical Spitz nevus/tumors (pASNT) is an emerging challenge in clinical dermatology and dermatopathology. Objective and Methods: We review the main clinicopathologic issues raised by pASNT and describe 2 examples of different clinicopathologic subsets of lesions. Results: While Spitz/Reed nevi are commonly small- to medium-sized, tan to black plaques, pASNT are large and nodular, either 'red' (dotted and/or polymorphous vascular pattern on dermoscopy; spindle and/or epithelioid tumors on histopathology: Spitz tumors, sensu strictiori) or 'blue' (homogeneous blue color on dermoscopy; intimate admixture of epithelioid cells and heavily pigmented dendritic cells on histopathology: Blitz tumors or pigmented epithelioid melanocytomas). Conclusions: Different clinicopathologic settings of pASNT probably exist. Dermoscopy can aid in their recognition and classification.",
keywords = "Atypical Spitz nevus/tumor, Dermoscopy, Histopathology, Spitz nevus",
author = "Gerardo Ferrara and Iris Zalaudek and Imma Savarese and Massimiliano Scalvenzi and Giuseppe Argenziano",
year = "2010",
doi = "10.1159/000300093",
language = "English",
volume = "220",
pages = "306--310",
journal = "Dermatology",
issn = "1018-8665",
publisher = "S. Karger AG",
number = "4",

}

TY - JOUR

T1 - Pediatric atypical spitzoid neoplasms

T2 - A review with emphasis on 'Red' ('Spitz') tumors and 'Blue' ('Blitz') tumors

AU - Ferrara, Gerardo

AU - Zalaudek, Iris

AU - Savarese, Imma

AU - Scalvenzi, Massimiliano

AU - Argenziano, Giuseppe

PY - 2010

Y1 - 2010

N2 - Background: The diagnosis of pediatric atypical Spitz nevus/tumors (pASNT) is an emerging challenge in clinical dermatology and dermatopathology. Objective and Methods: We review the main clinicopathologic issues raised by pASNT and describe 2 examples of different clinicopathologic subsets of lesions. Results: While Spitz/Reed nevi are commonly small- to medium-sized, tan to black plaques, pASNT are large and nodular, either 'red' (dotted and/or polymorphous vascular pattern on dermoscopy; spindle and/or epithelioid tumors on histopathology: Spitz tumors, sensu strictiori) or 'blue' (homogeneous blue color on dermoscopy; intimate admixture of epithelioid cells and heavily pigmented dendritic cells on histopathology: Blitz tumors or pigmented epithelioid melanocytomas). Conclusions: Different clinicopathologic settings of pASNT probably exist. Dermoscopy can aid in their recognition and classification.

AB - Background: The diagnosis of pediatric atypical Spitz nevus/tumors (pASNT) is an emerging challenge in clinical dermatology and dermatopathology. Objective and Methods: We review the main clinicopathologic issues raised by pASNT and describe 2 examples of different clinicopathologic subsets of lesions. Results: While Spitz/Reed nevi are commonly small- to medium-sized, tan to black plaques, pASNT are large and nodular, either 'red' (dotted and/or polymorphous vascular pattern on dermoscopy; spindle and/or epithelioid tumors on histopathology: Spitz tumors, sensu strictiori) or 'blue' (homogeneous blue color on dermoscopy; intimate admixture of epithelioid cells and heavily pigmented dendritic cells on histopathology: Blitz tumors or pigmented epithelioid melanocytomas). Conclusions: Different clinicopathologic settings of pASNT probably exist. Dermoscopy can aid in their recognition and classification.

KW - Atypical Spitz nevus/tumor

KW - Dermoscopy

KW - Histopathology

KW - Spitz nevus

UR - http://www.scopus.com/inward/record.url?scp=77954235170&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954235170&partnerID=8YFLogxK

U2 - 10.1159/000300093

DO - 10.1159/000300093

M3 - Article

C2 - 20453474

AN - SCOPUS:77954235170

VL - 220

SP - 306

EP - 310

JO - Dermatology

JF - Dermatology

SN - 1018-8665

IS - 4

ER -