This was an informative survey and the responses confirmed our impression that pediatric tumors are a challenge to everyone. There were some valuable individual observations about problematic morphology There are several general conclusions: 1) There are many tumors that do not fit into the present classification. 2) The WHO 2000 definitions of the large cell medulloblastoma, supratentorial PNET and ependymoblastoma are not widely utilized. 3) There are some tumors which should be studied to answer specific problems. a) Does a mixed pilocytic/diffuse astrocytoma behave differently than a pilocytic astrocytoma in the cerebellum, brain stem, cerebrum? b) Does the cerebral neuroblastoma behave differently than a supratentorial PNET? c) Does recurrent DNET represent growth of a residual lesion, or does it in fact recur? d) Does the ependymoblastoma behave differently than an anaplastic ependymoma. 4) There are some tumors, eg, ATRT where molecular testing serves as a critical and definitive diagnostic adjuvant.
|Number of pages||3|
|Publication status||Published - Jul 2003|
ASJC Scopus subject areas
- Pathology and Forensic Medicine