Pediatric bronchiectasis: Correlation of HRCT, ventilation and perfusion scintigraphy, and pulmonary function testing

Massimo Pifferi, Davide Caramella, Alessandra Bulleri, Simonetta Baldi, Diego Peroni, Angelo Pietrobelli, Attilio L. Boner

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Bronchiectasis in children, although occurring with diminished frequency, continues as a major challenge for the pediatric pulmonologist. The method of choice for the diagnosis of the condition is high-resolution computed tomography (HRCT). The aim of the present study was to correlate the relationship(s) of HRCT, lung function, ventilation lung scintigraphy (VLS), and perfusion lung scintigraphy (PLS) in children with bronchiectasis. Sixteen children ranging in age from 4-18 years with clinical and chest X-ray evidence of bronchiectasis were enrolled in the study. The degree of bronchiectasis was assessed by HRCT scores, decrease in attenuation on expiratory scans, VLS, and PLS. HRCT scores for bronchiectasis and decreased lung attenuation showed a strong correlation with PLS (p = 0.82; P <0.001) and with VLS (p = 0.72; P <0.01). There was a moderate negative correlation between FEV1 and HRCT bronchiectasis scores (p = -0.53; P= 0.02), decreased lung attenuation score (p = -0.64; P= 0.007), and atelectasis score (p = -0.54; P= 0.03). In conclusion, HRCT provides a complete and precise assessment of children with bronchiectasis. Ventilation/perfusion scans and lung functions are additive tools to understand the complexity of the disease process and to improve diagnosis and therapeutic strategies.

Original languageEnglish
Pages (from-to)298-303
Number of pages6
JournalPediatric Pulmonology
Volume38
Issue number4
DOIs
Publication statusPublished - Oct 2004

Fingerprint

Perfusion Imaging
Bronchiectasis
Ventilation
Tomography
Pediatrics
Lung
Radionuclide Imaging
Pulmonary Atelectasis
Thorax
Perfusion
X-Rays

Keywords

  • Bronchiectasis
  • Children
  • High-resolution computed tomography
  • Lung function
  • Ventilation/perfusion lung scintigraphy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

Pifferi, M., Caramella, D., Bulleri, A., Baldi, S., Peroni, D., Pietrobelli, A., & Boner, A. L. (2004). Pediatric bronchiectasis: Correlation of HRCT, ventilation and perfusion scintigraphy, and pulmonary function testing. Pediatric Pulmonology, 38(4), 298-303. https://doi.org/10.1002/ppul.20110

Pediatric bronchiectasis : Correlation of HRCT, ventilation and perfusion scintigraphy, and pulmonary function testing. / Pifferi, Massimo; Caramella, Davide; Bulleri, Alessandra; Baldi, Simonetta; Peroni, Diego; Pietrobelli, Angelo; Boner, Attilio L.

In: Pediatric Pulmonology, Vol. 38, No. 4, 10.2004, p. 298-303.

Research output: Contribution to journalArticle

Pifferi, M, Caramella, D, Bulleri, A, Baldi, S, Peroni, D, Pietrobelli, A & Boner, AL 2004, 'Pediatric bronchiectasis: Correlation of HRCT, ventilation and perfusion scintigraphy, and pulmonary function testing', Pediatric Pulmonology, vol. 38, no. 4, pp. 298-303. https://doi.org/10.1002/ppul.20110
Pifferi, Massimo ; Caramella, Davide ; Bulleri, Alessandra ; Baldi, Simonetta ; Peroni, Diego ; Pietrobelli, Angelo ; Boner, Attilio L. / Pediatric bronchiectasis : Correlation of HRCT, ventilation and perfusion scintigraphy, and pulmonary function testing. In: Pediatric Pulmonology. 2004 ; Vol. 38, No. 4. pp. 298-303.
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