Pediatric Chronic Intestinal Failure in Italy

Antonella Diamanti, Teresa Capriati, Paolo Gandullia, Grazia Di Leo, Antonella Lezo, Laura Lacitignola, Maria Immacolata Spagnuolo, Simona Gatti, Lorenzo D'Antiga, Giovanna Verlato, Paola Roggero, Sergio Amarri, Maria Elisabetta Baldassarre, Francesco Cirillo, Domenica Elia, Renata Boldrini, Angelo Campanozzi, Carlo Catassi, Marina Aloi, Claudio RomanoManila Candusso, Nicola Cecchi, Tommaso Bellini, Elaine Tyndall, Fabio Fusaro, Tamara Caldaro, Daniele Alberti, Piergiorgio Gamba, Mario Lima, Pietro Bagolan, Jean De Ville de Goyet, Luigi Dall'Oglio, Marco Spada, Francesca Grandi

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Abstract

BACKGROUND: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy.METHODS: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family's place of residence and underlying diagnosis determining IF.RESULTS: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20-18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53-2.20).CONCLUSION: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries.
Original languageEnglish
JournalNutrients
Volume9
Issue number11
DOIs
Publication statusPublished - Nov 5 2017

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parenteral feeding
Home Parenteral Nutrition
Italy
Pediatrics
Gastroenterology
child growth
incidence
surgeons
weight control
developed countries
digestive system
digestion
Incidence
nutrition
Developed Countries
gender
Digestion
nutrients
Maintenance
Research Personnel

Keywords

  • Journal Article

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Pediatric Chronic Intestinal Failure in Italy. / Diamanti, Antonella; Capriati, Teresa; Gandullia, Paolo; Di Leo, Grazia; Lezo, Antonella; Lacitignola, Laura; Spagnuolo, Maria Immacolata; Gatti, Simona; D'Antiga, Lorenzo; Verlato, Giovanna; Roggero, Paola; Amarri, Sergio; Baldassarre, Maria Elisabetta; Cirillo, Francesco; Elia, Domenica; Boldrini, Renata; Campanozzi, Angelo; Catassi, Carlo; Aloi, Marina; Romano, Claudio; Candusso, Manila; Cecchi, Nicola; Bellini, Tommaso; Tyndall, Elaine; Fusaro, Fabio; Caldaro, Tamara; Alberti, Daniele; Gamba, Piergiorgio; Lima, Mario; Bagolan, Pietro; De Ville de Goyet, Jean; Dall'Oglio, Luigi; Spada, Marco; Grandi, Francesca.

In: Nutrients, Vol. 9, No. 11, 05.11.2017.

Research output: Contribution to journalArticle

Diamanti, A, Capriati, T, Gandullia, P, Di Leo, G, Lezo, A, Lacitignola, L, Spagnuolo, MI, Gatti, S, D'Antiga, L, Verlato, G, Roggero, P, Amarri, S, Baldassarre, ME, Cirillo, F, Elia, D, Boldrini, R, Campanozzi, A, Catassi, C, Aloi, M, Romano, C, Candusso, M, Cecchi, N, Bellini, T, Tyndall, E, Fusaro, F, Caldaro, T, Alberti, D, Gamba, P, Lima, M, Bagolan, P, De Ville de Goyet, J, Dall'Oglio, L, Spada, M & Grandi, F 2017, 'Pediatric Chronic Intestinal Failure in Italy', Nutrients, vol. 9, no. 11. https://doi.org/10.3390/nu9111217
Diamanti, Antonella ; Capriati, Teresa ; Gandullia, Paolo ; Di Leo, Grazia ; Lezo, Antonella ; Lacitignola, Laura ; Spagnuolo, Maria Immacolata ; Gatti, Simona ; D'Antiga, Lorenzo ; Verlato, Giovanna ; Roggero, Paola ; Amarri, Sergio ; Baldassarre, Maria Elisabetta ; Cirillo, Francesco ; Elia, Domenica ; Boldrini, Renata ; Campanozzi, Angelo ; Catassi, Carlo ; Aloi, Marina ; Romano, Claudio ; Candusso, Manila ; Cecchi, Nicola ; Bellini, Tommaso ; Tyndall, Elaine ; Fusaro, Fabio ; Caldaro, Tamara ; Alberti, Daniele ; Gamba, Piergiorgio ; Lima, Mario ; Bagolan, Pietro ; De Ville de Goyet, Jean ; Dall'Oglio, Luigi ; Spada, Marco ; Grandi, Francesca. / Pediatric Chronic Intestinal Failure in Italy. In: Nutrients. 2017 ; Vol. 9, No. 11.
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TY - JOUR

T1 - Pediatric Chronic Intestinal Failure in Italy

AU - Diamanti, Antonella

AU - Capriati, Teresa

AU - Gandullia, Paolo

AU - Di Leo, Grazia

AU - Lezo, Antonella

AU - Lacitignola, Laura

AU - Spagnuolo, Maria Immacolata

AU - Gatti, Simona

AU - D'Antiga, Lorenzo

AU - Verlato, Giovanna

AU - Roggero, Paola

AU - Amarri, Sergio

AU - Baldassarre, Maria Elisabetta

AU - Cirillo, Francesco

AU - Elia, Domenica

AU - Boldrini, Renata

AU - Campanozzi, Angelo

AU - Catassi, Carlo

AU - Aloi, Marina

AU - Romano, Claudio

AU - Candusso, Manila

AU - Cecchi, Nicola

AU - Bellini, Tommaso

AU - Tyndall, Elaine

AU - Fusaro, Fabio

AU - Caldaro, Tamara

AU - Alberti, Daniele

AU - Gamba, Piergiorgio

AU - Lima, Mario

AU - Bagolan, Pietro

AU - De Ville de Goyet, Jean

AU - Dall'Oglio, Luigi

AU - Spada, Marco

AU - Grandi, Francesca

PY - 2017/11/5

Y1 - 2017/11/5

N2 - BACKGROUND: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy.METHODS: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family's place of residence and underlying diagnosis determining IF.RESULTS: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20-18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53-2.20).CONCLUSION: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries.

AB - BACKGROUND: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy.METHODS: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family's place of residence and underlying diagnosis determining IF.RESULTS: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20-18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53-2.20).CONCLUSION: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries.

KW - Journal Article

U2 - 10.3390/nu9111217

DO - 10.3390/nu9111217

M3 - Article

VL - 9

JO - Nutrients

JF - Nutrients

SN - 2072-6643

IS - 11

ER -