Abstract
Background: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy. Methods: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family’s place of residence and underlying diagnosis determining IF. Results: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20–18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53–2.20). Conclusion: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries.
| Original language | English |
|---|---|
| Article number | 1217 |
| Journal | Nutrients |
| Volume | 9 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Nov 1 2017 |
Fingerprint
Keywords
- Children
- Home parenteral nutrition
- Intestinal failure
ASJC Scopus subject areas
- Food Science
- Nutrition and Dietetics
Cite this
Pediatric chronic intestinal failure in italy : Report from the 2016 survey on behalf of Italian society for gastroenterology, hepatology and nutrition (SIGENP). / Diamanti, Antonella; Capriati, Teresa; Gandullia, Paolo; Dileo, Grazia; Lezo, Antonella; Lacitignola, Laura; Spagnuolo, Mariaimmacolata; Gatti, Simona; D’Antiga, Lorenzo; Verlato, Giovanna; Roggero, Paola; Amarri, Sergio; Baldassarre, Mariaelisabetta; Cirillo, Francesco; Elia, Domenica; Boldrini, Renata; Campanozzi, Angelo; Catassi, Carlo; Aloi, Marina; Romano, Claudio; Candusso, Manila; Cecchi, Nicola; Bellini, Tommaso; Tyndall, Elaine; Fusaro, Fabio; Caldaro, Tamara; Alberti, Daniele; Gamba, Piergiorgio; Lima, Mario; Bagolan, Pietro; De Goyet, Jean De Ville; Dall’Oglio, Luigi; Spada, Marco; Grandi, Francesca.
In: Nutrients, Vol. 9, No. 11, 1217, 01.11.2017.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Pediatric chronic intestinal failure in italy
T2 - Report from the 2016 survey on behalf of Italian society for gastroenterology, hepatology and nutrition (SIGENP)
AU - Diamanti, Antonella
AU - Capriati, Teresa
AU - Gandullia, Paolo
AU - Dileo, Grazia
AU - Lezo, Antonella
AU - Lacitignola, Laura
AU - Spagnuolo, Mariaimmacolata
AU - Gatti, Simona
AU - D’Antiga, Lorenzo
AU - Verlato, Giovanna
AU - Roggero, Paola
AU - Amarri, Sergio
AU - Baldassarre, Mariaelisabetta
AU - Cirillo, Francesco
AU - Elia, Domenica
AU - Boldrini, Renata
AU - Campanozzi, Angelo
AU - Catassi, Carlo
AU - Aloi, Marina
AU - Romano, Claudio
AU - Candusso, Manila
AU - Cecchi, Nicola
AU - Bellini, Tommaso
AU - Tyndall, Elaine
AU - Fusaro, Fabio
AU - Caldaro, Tamara
AU - Alberti, Daniele
AU - Gamba, Piergiorgio
AU - Lima, Mario
AU - Bagolan, Pietro
AU - De Goyet, Jean De Ville
AU - Dall’Oglio, Luigi
AU - Spada, Marco
AU - Grandi, Francesca
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Background: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy. Methods: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family’s place of residence and underlying diagnosis determining IF. Results: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20–18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53–2.20). Conclusion: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries.
AB - Background: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy. Methods: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family’s place of residence and underlying diagnosis determining IF. Results: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20–18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53–2.20). Conclusion: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries.
KW - Children
KW - Home parenteral nutrition
KW - Intestinal failure
UR - http://www.scopus.com/inward/record.url?scp=85033436066&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85033436066&partnerID=8YFLogxK
U2 - 10.3390/nu9111217
DO - 10.3390/nu9111217
M3 - Review article
AN - SCOPUS:85033436066
VL - 9
JO - Nutrients
JF - Nutrients
SN - 2072-6643
IS - 11
M1 - 1217
ER -