Pediatric Index of Mortality 2 score in Italy: A multicenter, prospective, observational study

Andrea Wolfler, Paolo Silvani, Massimo Musicco, Ida Salvo, P. Vitale, A. Conio, G. Ottonello, A. Arena, C. Gallini, R. Gilodi, R. Osello, F. Ferrero, E. Zoia, A. Mandelli, L. Napolitano, S. Leoncino, E. Galassini, D. Codazzi, A. Baraldi, S. MolinaroP. Santuz, P. Cogo, A. Pettenazzo, L. Meneghini, F. Giusti, A. Sarti, E. Iannella, S. Baroncini, M. Calamandrei, A. Messeri, M. Marano, C. Tomasello, A. Onofri, M. Ferrari, M. Piastra, E. Caresta, A. Dolcini, C. Rovella, A. M. Guddo, M. Astuto, N. Disma, D. Salvo, D. Buono

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Objectives: To assess the performance of the Pediatric Index of Mortality (PIM) 2 score in Italian pediatric intensive care units (PICUs). Prospective, observational, multicenter, 1-year study. Setting: Eighteen medical-surgical PICUs. Patients: Consecutive patients (3266) aged 0-16 years admitted between 1 March 2004 and 28 February 2005. Interventions: None. Measurements and main results: To assess the performance of the PIM2 score, discrimination and calibration measures were applied to all children admitted to the 18 PICUs, in the entire population and in different groups divided for deciles of risk, age and admission diagnosis. There was good discrimination, with an area under the receiver operating characteristic (ROC) curve of 0.89 (95% CI 0.86-0.91) and good calibration of the scoring system [non-significant differences between observed and predicted deaths when the population was stratified according to deciles of risk (χ2 9.86; 8 df, p = 0.26) for the whole population]. Conclusions: The PIM2 score performed well in this sample of the Italian pediatric intensive care population. It may need to be reassessed in the injury and postoperative groups in larger studies.

Original languageEnglish
Pages (from-to)1407-1413
Number of pages7
JournalIntensive Care Medicine
Volume33
Issue number8
DOIs
Publication statusPublished - Aug 2007

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Pediatric Intensive Care Units
Italy
Observational Studies
Prospective Studies
Pediatrics
Mortality
Critical Care
Calibration
Population
ROC Curve
Wounds and Injuries

Keywords

  • Children
  • Mortality
  • Pediatric index of Mortality
  • Pediatric intensive care unit
  • Severity score

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Wolfler, A., Silvani, P., Musicco, M., Salvo, I., Vitale, P., Conio, A., ... Buono, D. (2007). Pediatric Index of Mortality 2 score in Italy: A multicenter, prospective, observational study. Intensive Care Medicine, 33(8), 1407-1413. https://doi.org/10.1007/s00134-007-0694-z

Pediatric Index of Mortality 2 score in Italy : A multicenter, prospective, observational study. / Wolfler, Andrea; Silvani, Paolo; Musicco, Massimo; Salvo, Ida; Vitale, P.; Conio, A.; Ottonello, G.; Arena, A.; Gallini, C.; Gilodi, R.; Osello, R.; Ferrero, F.; Zoia, E.; Mandelli, A.; Napolitano, L.; Leoncino, S.; Galassini, E.; Codazzi, D.; Baraldi, A.; Molinaro, S.; Santuz, P.; Cogo, P.; Pettenazzo, A.; Meneghini, L.; Giusti, F.; Sarti, A.; Iannella, E.; Baroncini, S.; Calamandrei, M.; Messeri, A.; Marano, M.; Tomasello, C.; Onofri, A.; Ferrari, M.; Piastra, M.; Caresta, E.; Dolcini, A.; Rovella, C.; Guddo, A. M.; Astuto, M.; Disma, N.; Salvo, D.; Buono, D.

In: Intensive Care Medicine, Vol. 33, No. 8, 08.2007, p. 1407-1413.

Research output: Contribution to journalArticle

Wolfler, A, Silvani, P, Musicco, M, Salvo, I, Vitale, P, Conio, A, Ottonello, G, Arena, A, Gallini, C, Gilodi, R, Osello, R, Ferrero, F, Zoia, E, Mandelli, A, Napolitano, L, Leoncino, S, Galassini, E, Codazzi, D, Baraldi, A, Molinaro, S, Santuz, P, Cogo, P, Pettenazzo, A, Meneghini, L, Giusti, F, Sarti, A, Iannella, E, Baroncini, S, Calamandrei, M, Messeri, A, Marano, M, Tomasello, C, Onofri, A, Ferrari, M, Piastra, M, Caresta, E, Dolcini, A, Rovella, C, Guddo, AM, Astuto, M, Disma, N, Salvo, D & Buono, D 2007, 'Pediatric Index of Mortality 2 score in Italy: A multicenter, prospective, observational study', Intensive Care Medicine, vol. 33, no. 8, pp. 1407-1413. https://doi.org/10.1007/s00134-007-0694-z
Wolfler, Andrea ; Silvani, Paolo ; Musicco, Massimo ; Salvo, Ida ; Vitale, P. ; Conio, A. ; Ottonello, G. ; Arena, A. ; Gallini, C. ; Gilodi, R. ; Osello, R. ; Ferrero, F. ; Zoia, E. ; Mandelli, A. ; Napolitano, L. ; Leoncino, S. ; Galassini, E. ; Codazzi, D. ; Baraldi, A. ; Molinaro, S. ; Santuz, P. ; Cogo, P. ; Pettenazzo, A. ; Meneghini, L. ; Giusti, F. ; Sarti, A. ; Iannella, E. ; Baroncini, S. ; Calamandrei, M. ; Messeri, A. ; Marano, M. ; Tomasello, C. ; Onofri, A. ; Ferrari, M. ; Piastra, M. ; Caresta, E. ; Dolcini, A. ; Rovella, C. ; Guddo, A. M. ; Astuto, M. ; Disma, N. ; Salvo, D. ; Buono, D. / Pediatric Index of Mortality 2 score in Italy : A multicenter, prospective, observational study. In: Intensive Care Medicine. 2007 ; Vol. 33, No. 8. pp. 1407-1413.
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abstract = "Objectives: To assess the performance of the Pediatric Index of Mortality (PIM) 2 score in Italian pediatric intensive care units (PICUs). Prospective, observational, multicenter, 1-year study. Setting: Eighteen medical-surgical PICUs. Patients: Consecutive patients (3266) aged 0-16 years admitted between 1 March 2004 and 28 February 2005. Interventions: None. Measurements and main results: To assess the performance of the PIM2 score, discrimination and calibration measures were applied to all children admitted to the 18 PICUs, in the entire population and in different groups divided for deciles of risk, age and admission diagnosis. There was good discrimination, with an area under the receiver operating characteristic (ROC) curve of 0.89 (95{\%} CI 0.86-0.91) and good calibration of the scoring system [non-significant differences between observed and predicted deaths when the population was stratified according to deciles of risk (χ2 9.86; 8 df, p = 0.26) for the whole population]. Conclusions: The PIM2 score performed well in this sample of the Italian pediatric intensive care population. It may need to be reassessed in the injury and postoperative groups in larger studies.",
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T2 - A multicenter, prospective, observational study

AU - Wolfler, Andrea

AU - Silvani, Paolo

AU - Musicco, Massimo

AU - Salvo, Ida

AU - Vitale, P.

AU - Conio, A.

AU - Ottonello, G.

AU - Arena, A.

AU - Gallini, C.

AU - Gilodi, R.

AU - Osello, R.

AU - Ferrero, F.

AU - Zoia, E.

AU - Mandelli, A.

AU - Napolitano, L.

AU - Leoncino, S.

AU - Galassini, E.

AU - Codazzi, D.

AU - Baraldi, A.

AU - Molinaro, S.

AU - Santuz, P.

AU - Cogo, P.

AU - Pettenazzo, A.

AU - Meneghini, L.

AU - Giusti, F.

AU - Sarti, A.

AU - Iannella, E.

AU - Baroncini, S.

AU - Calamandrei, M.

AU - Messeri, A.

AU - Marano, M.

AU - Tomasello, C.

AU - Onofri, A.

AU - Ferrari, M.

AU - Piastra, M.

AU - Caresta, E.

AU - Dolcini, A.

AU - Rovella, C.

AU - Guddo, A. M.

AU - Astuto, M.

AU - Disma, N.

AU - Salvo, D.

AU - Buono, D.

PY - 2007/8

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N2 - Objectives: To assess the performance of the Pediatric Index of Mortality (PIM) 2 score in Italian pediatric intensive care units (PICUs). Prospective, observational, multicenter, 1-year study. Setting: Eighteen medical-surgical PICUs. Patients: Consecutive patients (3266) aged 0-16 years admitted between 1 March 2004 and 28 February 2005. Interventions: None. Measurements and main results: To assess the performance of the PIM2 score, discrimination and calibration measures were applied to all children admitted to the 18 PICUs, in the entire population and in different groups divided for deciles of risk, age and admission diagnosis. There was good discrimination, with an area under the receiver operating characteristic (ROC) curve of 0.89 (95% CI 0.86-0.91) and good calibration of the scoring system [non-significant differences between observed and predicted deaths when the population was stratified according to deciles of risk (χ2 9.86; 8 df, p = 0.26) for the whole population]. Conclusions: The PIM2 score performed well in this sample of the Italian pediatric intensive care population. It may need to be reassessed in the injury and postoperative groups in larger studies.

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KW - Severity score

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