Pediatric inflammatory diseases. Part I

multiple sclerosis

A. Catalucci, M. Anselmi, A. Splendiani, J. D. Smith, N. Limbucci, F. Giangaspero, Massimo Gallucci

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Multiple sclerosis (MS) is an inflammatory CNS disease characterized by multifocal areas of demyelination; usually it arises in young adults, but can also occur in children (under the age of 10) and adolescents (under the age of 18). As in adult, pediatric MS (PMS) diagnosis is based on the demonstration of multiple demyelination episodes separated in time and spaces. Diagnostic criteria realized for childhood are similar to those employed for adults. Although clinical and imaging features of PMS can be similar to those of adults, the disease is often characterized by a more aggressive course and atypical imaging findings, with giant and pseudotumoral plaques. Differential diagnosis between PMS and ADEM could be difficult: clinical findings and MRI are necessary; sometimes MRI follow-up is required for definitive diagnosis.

Original languageEnglish
Pages (from-to)684-694
Number of pages11
JournalNeuroradiology Journal
Volume25
Issue number6
Publication statusPublished - Dec 2012

Fingerprint

Multiple Sclerosis
Demyelinating Diseases
Pediatrics
Central Nervous System Diseases
Young Adult
Differential Diagnosis

Keywords

  • Giant plaques
  • MRI
  • Pediatric multiple sclerosis (PMS)

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

Cite this

Catalucci, A., Anselmi, M., Splendiani, A., Smith, J. D., Limbucci, N., Giangaspero, F., & Gallucci, M. (2012). Pediatric inflammatory diseases. Part I: multiple sclerosis. Neuroradiology Journal, 25(6), 684-694.

Pediatric inflammatory diseases. Part I : multiple sclerosis. / Catalucci, A.; Anselmi, M.; Splendiani, A.; Smith, J. D.; Limbucci, N.; Giangaspero, F.; Gallucci, Massimo.

In: Neuroradiology Journal, Vol. 25, No. 6, 12.2012, p. 684-694.

Research output: Contribution to journalArticle

Catalucci, A, Anselmi, M, Splendiani, A, Smith, JD, Limbucci, N, Giangaspero, F & Gallucci, M 2012, 'Pediatric inflammatory diseases. Part I: multiple sclerosis', Neuroradiology Journal, vol. 25, no. 6, pp. 684-694.
Catalucci A, Anselmi M, Splendiani A, Smith JD, Limbucci N, Giangaspero F et al. Pediatric inflammatory diseases. Part I: multiple sclerosis. Neuroradiology Journal. 2012 Dec;25(6):684-694.
Catalucci, A. ; Anselmi, M. ; Splendiani, A. ; Smith, J. D. ; Limbucci, N. ; Giangaspero, F. ; Gallucci, Massimo. / Pediatric inflammatory diseases. Part I : multiple sclerosis. In: Neuroradiology Journal. 2012 ; Vol. 25, No. 6. pp. 684-694.
@article{4b34105a84054ab89dde1cd5affc3fcc,
title = "Pediatric inflammatory diseases. Part I: multiple sclerosis",
abstract = "Multiple sclerosis (MS) is an inflammatory CNS disease characterized by multifocal areas of demyelination; usually it arises in young adults, but can also occur in children (under the age of 10) and adolescents (under the age of 18). As in adult, pediatric MS (PMS) diagnosis is based on the demonstration of multiple demyelination episodes separated in time and spaces. Diagnostic criteria realized for childhood are similar to those employed for adults. Although clinical and imaging features of PMS can be similar to those of adults, the disease is often characterized by a more aggressive course and atypical imaging findings, with giant and pseudotumoral plaques. Differential diagnosis between PMS and ADEM could be difficult: clinical findings and MRI are necessary; sometimes MRI follow-up is required for definitive diagnosis.",
keywords = "Giant plaques, MRI, Pediatric multiple sclerosis (PMS)",
author = "A. Catalucci and M. Anselmi and A. Splendiani and Smith, {J. D.} and N. Limbucci and F. Giangaspero and Massimo Gallucci",
year = "2012",
month = "12",
language = "English",
volume = "25",
pages = "684--694",
journal = "Neuroradiology Journal",
issn = "1971-4009",
publisher = "Centauro srl",
number = "6",

}

TY - JOUR

T1 - Pediatric inflammatory diseases. Part I

T2 - multiple sclerosis

AU - Catalucci, A.

AU - Anselmi, M.

AU - Splendiani, A.

AU - Smith, J. D.

AU - Limbucci, N.

AU - Giangaspero, F.

AU - Gallucci, Massimo

PY - 2012/12

Y1 - 2012/12

N2 - Multiple sclerosis (MS) is an inflammatory CNS disease characterized by multifocal areas of demyelination; usually it arises in young adults, but can also occur in children (under the age of 10) and adolescents (under the age of 18). As in adult, pediatric MS (PMS) diagnosis is based on the demonstration of multiple demyelination episodes separated in time and spaces. Diagnostic criteria realized for childhood are similar to those employed for adults. Although clinical and imaging features of PMS can be similar to those of adults, the disease is often characterized by a more aggressive course and atypical imaging findings, with giant and pseudotumoral plaques. Differential diagnosis between PMS and ADEM could be difficult: clinical findings and MRI are necessary; sometimes MRI follow-up is required for definitive diagnosis.

AB - Multiple sclerosis (MS) is an inflammatory CNS disease characterized by multifocal areas of demyelination; usually it arises in young adults, but can also occur in children (under the age of 10) and adolescents (under the age of 18). As in adult, pediatric MS (PMS) diagnosis is based on the demonstration of multiple demyelination episodes separated in time and spaces. Diagnostic criteria realized for childhood are similar to those employed for adults. Although clinical and imaging features of PMS can be similar to those of adults, the disease is often characterized by a more aggressive course and atypical imaging findings, with giant and pseudotumoral plaques. Differential diagnosis between PMS and ADEM could be difficult: clinical findings and MRI are necessary; sometimes MRI follow-up is required for definitive diagnosis.

KW - Giant plaques

KW - MRI

KW - Pediatric multiple sclerosis (PMS)

UR - http://www.scopus.com/inward/record.url?scp=84872738249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872738249&partnerID=8YFLogxK

M3 - Article

VL - 25

SP - 684

EP - 694

JO - Neuroradiology Journal

JF - Neuroradiology Journal

SN - 1971-4009

IS - 6

ER -