Pediatric liver transplantation

Marco Spada, Silvia Riva, Giuseppe Maggiore, Davide Cintorino, Bruno Gridelli

Research output: Contribution to journalArticle

Abstract

In previous decades, pediatric liver transplantation has become a state-of-the-art operation with excellent success and limited mortality. Graft and patient survival have continued to improve as a result of improvements in medical, surgical and anesthetic management, organ availability, immunosuppression, and identification and treatment of postoperative complications. The utilization of split-liver grafts and living-related donors has provided more organs for pediatric patients. Newer immunosuppression regimens, including induction therapy, have had a significant impact on graft and patient survival. Future developments of pediatric liver transplantation will deal with long-term follow-up, with prevention of immunosuppression-related complications and promotion of as normal growth as possible. This review describes the state-of-the-art in pediatric liver transplantation.

Original languageEnglish
Pages (from-to)648-674
Number of pages27
JournalWorld Journal of Gastroenterology
Volume15
Issue number6
DOIs
Publication statusPublished - Feb 14 2009

Keywords

  • Complications
  • Indications
  • Pediatric liver transplantation
  • Surgical techniques

ASJC Scopus subject areas

  • Gastroenterology

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