TY - JOUR
T1 - Pediatric Nonalcoholic Fatty Liver Disease in 2009
AU - Alisi, Anna
AU - Manco, Melania
AU - Vania, Andrea
AU - Nobili, Valerio
PY - 2009/10
Y1 - 2009/10
N2 - Over the last decade, there has been a growing recognition of NAFLD as pediatric disease. In view of the lack of longitudinal studies describing the natural history of the disease and, particularly, poor diagnostic means of distinguishing benign from progressive forms, it is important to prevent fatty liver in children and attempt to intervene as soon as it is suspected. Promoting physical activity and healthy eating early in the lives of children may decrease the risk of NAFLD. In the early preschool years, parents should be educated to include healthy food choices and active play into the lifestyles of their entire families. Obese children presenting with concurrent metabolic abnormalities merit at the very least an assay of liver enzyme and ultrasound evaluation for fatty liver. Monitoring of liver histology can be worthwhile in extremely obese children with severely impaired metabolism, because they may develop fibrosis and hepatic insufficiency as young adults.
AB - Over the last decade, there has been a growing recognition of NAFLD as pediatric disease. In view of the lack of longitudinal studies describing the natural history of the disease and, particularly, poor diagnostic means of distinguishing benign from progressive forms, it is important to prevent fatty liver in children and attempt to intervene as soon as it is suspected. Promoting physical activity and healthy eating early in the lives of children may decrease the risk of NAFLD. In the early preschool years, parents should be educated to include healthy food choices and active play into the lifestyles of their entire families. Obese children presenting with concurrent metabolic abnormalities merit at the very least an assay of liver enzyme and ultrasound evaluation for fatty liver. Monitoring of liver histology can be worthwhile in extremely obese children with severely impaired metabolism, because they may develop fibrosis and hepatic insufficiency as young adults.
UR - http://www.scopus.com/inward/record.url?scp=70249094340&partnerID=8YFLogxK
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U2 - 10.1016/j.jpeds.2009.06.014
DO - 10.1016/j.jpeds.2009.06.014
M3 - Article
C2 - 19772998
AN - SCOPUS:70249094340
VL - 155
SP - 469
EP - 474
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 4
ER -