Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Giulio Kleiner; Valentina Zanin; Lorenzo Monasta; Sergio Crovella; Lorenzo Caruso; Daniela Milani; Annalisa Marcuzzi

doi:10.3892/etm.2015.2370

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Giulio Kleiner, Valentina Zanin, Lorenzo Monasta, Sergio Crovella, Lorenzo Caruso, Daniela Milani, Annalisa Marcuzzi

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory condition of the gastrointestinal tract. Although the causative events that lead to the onset of IBD are yet to be fully elucidated, deregulation of immune and inflammatory mechanisms are hypothesized to significantly contribute to this disorder. Since the onset of IBD is often during infancy, in the present study, the serum values of a large panel of cytokines and chemokines in pediatric patients (

Original language	English
Pages (from-to)	2047-2052
Number of pages	6
Journal	Experimental and Therapeutic Medicine
Volume	9
Issue number	6
DOIs	https://doi.org/10.3892/etm.2015.2370
Publication status	Published - 2015

Keywords

Chemokines
Cytokines
Inflammatory bowel disease

ASJC Scopus subject areas

Medicine(all)
Cancer Research
Immunology and Microbiology (miscellaneous)

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10.3892/etm.2015.2370

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Kleiner, G., Zanin, V., Monasta, L., Crovella, S., Caruso, L., Milani, D., & Marcuzzi, A. (2015). Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. Experimental and Therapeutic Medicine, 9(6), 2047-2052. https://doi.org/10.3892/etm.2015.2370

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. / Kleiner, Giulio; Zanin, Valentina; Monasta, Lorenzo ; Crovella, Sergio; Caruso, Lorenzo; Milani, Daniela; Marcuzzi, Annalisa.

In: Experimental and Therapeutic Medicine, Vol. 9, No. 6, 2015, p. 2047-2052.

Research output: Contribution to journal › Article › peer-review

Kleiner, G, Zanin, V, Monasta, L , Crovella, S, Caruso, L, Milani, D & Marcuzzi, A 2015, 'Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17', Experimental and Therapeutic Medicine, vol. 9, no. 6, pp. 2047-2052. https://doi.org/10.3892/etm.2015.2370

Kleiner G, Zanin V, Monasta L , Crovella S, Caruso L, Milani D et al. Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. Experimental and Therapeutic Medicine. 2015;9(6):2047-2052. https://doi.org/10.3892/etm.2015.2370

Kleiner, Giulio ; Zanin, Valentina ; Monasta, Lorenzo ; Crovella, Sergio ; Caruso, Lorenzo ; Milani, Daniela ; Marcuzzi, Annalisa. / Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. In: Experimental and Therapeutic Medicine. 2015 ; Vol. 9, No. 6. pp. 2047-2052.

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Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Abstract

Keywords

ASJC Scopus subject areas

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