Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Giulio Kleiner; Valentina Zanin; Lorenzo Monasta; Sergio Crovella; Lorenzo Caruso; Daniela Milani; Annalisa Marcuzzi

doi:10.3892/etm.2015.2370

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Giulio Kleiner, Valentina Zanin, Lorenzo Monasta, Sergio Crovella, Lorenzo Caruso, Daniela Milani, Annalisa Marcuzzi

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory condition of the gastrointestinal tract. Although the causative events that lead to the onset of IBD are yet to be fully elucidated, deregulation of immune and inflammatory mechanisms are hypothesized to significantly contribute to this disorder. Since the onset of IBD is often during infancy, in the present study, the serum values of a large panel of cytokines and chemokines in pediatric patients (

Original language	English
Pages (from-to)	2047-2052
Number of pages	6
Journal	Experimental and Therapeutic Medicine
Volume	9
Issue number	6
DOIs	https://doi.org/10.3892/etm.2015.2370
Publication status	Published - 2015

Keywords

Chemokines
Cytokines
Inflammatory bowel disease

ASJC Scopus subject areas

Medicine(all)
Cancer Research
Immunology and Microbiology (miscellaneous)

Access to Document

10.3892/etm.2015.2370

Fingerprint Dive into the research topics of 'Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17'. Together they form a unique fingerprint.

Cite this

Kleiner, G., Zanin, V., Monasta, L., Crovella, S., Caruso, L., Milani, D., & Marcuzzi, A. (2015). Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. Experimental and Therapeutic Medicine, 9(6), 2047-2052. https://doi.org/10.3892/etm.2015.2370

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. / Kleiner, Giulio; Zanin, Valentina; Monasta, Lorenzo ; Crovella, Sergio; Caruso, Lorenzo; Milani, Daniela; Marcuzzi, Annalisa.

In: Experimental and Therapeutic Medicine, Vol. 9, No. 6, 2015, p. 2047-2052.

Research output: Contribution to journal › Article › peer-review

Kleiner, G, Zanin, V, Monasta, L , Crovella, S, Caruso, L, Milani, D & Marcuzzi, A 2015, 'Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17', Experimental and Therapeutic Medicine, vol. 9, no. 6, pp. 2047-2052. https://doi.org/10.3892/etm.2015.2370

Kleiner G, Zanin V, Monasta L , Crovella S, Caruso L, Milani D et al. Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. Experimental and Therapeutic Medicine. 2015;9(6):2047-2052. https://doi.org/10.3892/etm.2015.2370

Kleiner, Giulio ; Zanin, Valentina ; Monasta, Lorenzo ; Crovella, Sergio ; Caruso, Lorenzo ; Milani, Daniela ; Marcuzzi, Annalisa. / Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17. In: Experimental and Therapeutic Medicine. 2015 ; Vol. 9, No. 6. pp. 2047-2052.

@article{b2171a1fdb9346ac930f034c478200e3,

title = "Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17",

abstract = "Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory condition of the gastrointestinal tract. Although the causative events that lead to the onset of IBD are yet to be fully elucidated, deregulation of immune and inflammatory mechanisms are hypothesized to significantly contribute to this disorder. Since the onset of IBD is often during infancy, in the present study, the serum values of a large panel of cytokines and chemokines in pediatric patients (",

keywords = "Chemokines, Cytokines, Inflammatory bowel disease",

author = "Giulio Kleiner and Valentina Zanin and Lorenzo Monasta and Sergio Crovella and Lorenzo Caruso and Daniela Milani and Annalisa Marcuzzi",

year = "2015",

doi = "10.3892/etm.2015.2370",

language = "English",

volume = "9",

pages = "2047--2052",

journal = "Experimental and Therapeutic Medicine",

issn = "1792-0981",

publisher = "Spandidos Publications",

number = "6",

}

TY - JOUR

T1 - Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

AU - Kleiner, Giulio

AU - Zanin, Valentina

AU - Monasta, Lorenzo

AU - Crovella, Sergio

AU - Caruso, Lorenzo

AU - Milani, Daniela

AU - Marcuzzi, Annalisa

PY - 2015

Y1 - 2015

N2 - Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory condition of the gastrointestinal tract. Although the causative events that lead to the onset of IBD are yet to be fully elucidated, deregulation of immune and inflammatory mechanisms are hypothesized to significantly contribute to this disorder. Since the onset of IBD is often during infancy, in the present study, the serum values of a large panel of cytokines and chemokines in pediatric patients (

AB - Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory condition of the gastrointestinal tract. Although the causative events that lead to the onset of IBD are yet to be fully elucidated, deregulation of immune and inflammatory mechanisms are hypothesized to significantly contribute to this disorder. Since the onset of IBD is often during infancy, in the present study, the serum values of a large panel of cytokines and chemokines in pediatric patients (

KW - Chemokines

KW - Cytokines

KW - Inflammatory bowel disease

UR - http://www.scopus.com/inward/record.url?scp=84928254122&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928254122&partnerID=8YFLogxK

U2 - 10.3892/etm.2015.2370

DO - 10.3892/etm.2015.2370

M3 - Article

AN - SCOPUS:84928254122

VL - 9

SP - 2047

EP - 2052

JO - Experimental and Therapeutic Medicine

JF - Experimental and Therapeutic Medicine

SN - 1792-0981

IS - 6

ER -

Pediatric patients with inflammatory bowel disease exhibit increased serum levels of proinflammatory cytokines and chemokines, but decreased circulating levels of macrophage inhibitory protein-1β, interleukin-2 and interleukin-17

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this