Peliosis hepatis as an early histological finding in idiopathic portal hypertension: A case report

Annalisa Berzigotti, Donatella Magalotti, Paola Zappoli, Cristina Rossi, Francesco Callea, Marco Zoli

Research output: Contribution to journalArticle

Abstract

20 Peliosis hepatis is a rare condition characterized by dilatation of hepatic sinusoids and blood-filled spaces in the liver mainly observed in subjects exposed to toxic substances or estrogens, which is frequently asymptomatic. Non-cirrhotic idiopathic portal hypertension (NCIPH) is also a vascular disease of the liver rarely observed in European countries, which is usually diagnosed only when the hemorrhagic complications of portal hypertension occur. We report a case of NCIPH in a young Caucasian male who was diagnosed with liver peliosis, showing ultrasonographic and endoscopic signs of portal hypertension four years after. A second biopsy was diagnostic for NCIPH. Even if the pathogenesis remains obscure, peliosis hepatis can be considered as an early sign of vascular disease of the liver, which may progress to more definite conditions.

Original languageEnglish
Pages (from-to)3612-3615
Number of pages4
JournalWorld Journal of Gastroenterology
Volume12
Issue number22
Publication statusPublished - Jun 14 2006

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Keywords

  • Hepatic veins catheterisation
  • Idiopathic portal hypertension
  • Peliosis hepatis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Berzigotti, A., Magalotti, D., Zappoli, P., Rossi, C., Callea, F., & Zoli, M. (2006). Peliosis hepatis as an early histological finding in idiopathic portal hypertension: A case report. World Journal of Gastroenterology, 12(22), 3612-3615.