Pelvic dysfunctions and quality of life after nerve-sparing radical hysterectomy: A multicenter comparative study

Marcello Ceccaroni, Giovanni Roviglione, Emanuela Spagnolo, Paolo Casadio, Roberto Clarizia, Michele Peiretti, Francesco Bruni, Inge Peters, Giovanni Aletti

Research output: Contribution to journalArticle

Abstract

Aim: To analyze pelvic dysfunctions, quality of life, and survival after nerve-sparing radical hysterectomy (NSRH) compared to classical radical hysterectomy (RH) for cervical cancer. Patients and Methods: All cervical cancer patients undergoing a RH or a NSRH were evaluated for pelvic dysfunctions and filled in a quality-of-life questionnaire. Results: A total of 56 women were included; 31 underwent RH (group 1) and 25 NSRH (group 2). Postoperatively, a higher number of patients had urinary incontinence (p=0.02), urinary retention (p=0.01), faecal incontinence (p=0.01) and constipation (p=0.01) in group 1 versus group 2. Patients referred a higher rate of severe sexual dysfunction after RH compared to NSRH (p=0.03). No differences were found in orgasmic frequency and sexual desire; overall quality of life evaluation was more satisfactory after NSRH. Conclusion: NSRH conferred a better clinical outcome with fewer long-term bladder, colorectal and sexual complications. Post-operative quality of life after NSRH was better, with the same overall survival as compared to RH.

Original languageEnglish
Pages (from-to)581-588
Number of pages8
JournalAnticancer Research
Volume32
Issue number2
Publication statusPublished - Feb 2012

Keywords

  • Cervical cancer
  • Laparoscopy
  • Nerve-sparing
  • Pelvic dysfunctions
  • Quality of life
  • Radical hysterectomy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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  • Cite this

    Ceccaroni, M., Roviglione, G., Spagnolo, E., Casadio, P., Clarizia, R., Peiretti, M., Bruni, F., Peters, I., & Aletti, G. (2012). Pelvic dysfunctions and quality of life after nerve-sparing radical hysterectomy: A multicenter comparative study. Anticancer Research, 32(2), 581-588.