Penile pharmacotesting in diagnosing male erectile dysfunction: Evidence for lack of accuracy and specificity

Antonio Aversa, Andrea M. Isidori, Massimiliano Caprio, Marco Cerilli, Vanni Frajese, Andrea Fabbri

Research output: Contribution to journalArticlepeer-review

Abstract

Penile pharmacotesting (PPT) with alprostadil (PGE1) represents the most common diagnostic approach to male erectile dysfunction (ED). A positive response - i.e. normal erectile rigidity of sustained duration - is presumed to exclude venous or arterial pathology with enough accuracy. To test this assumption we compared PPT vs. flowmetric results obtained by colour-duplex Doppler ultrasound (CDDU) in patients (pts) undergoing diagnostic evaluation for ED under conditions of maximal cavernous relaxation. A total of 195 non-consecutive impotent pts were diagnosed after dynamic CDDU as non-vasculogenic (NOR), or having arteriogenic (AR), veno-occlusive (VO) or mixed (MX) ED. Maximal erection obtained after PPT was scored as: type-1 (full tumescence - no sustained rigidity, angle on the abdominal plane >90°), type-2 (sustained partial erection, valid for intromission, angle= 90°) and type-3 (sustained full erection, angle

Original languageEnglish
Pages (from-to)6-10
Number of pages5
JournalInternational Journal of Andrology
Volume25
Issue number1
DOIs
Publication statusPublished - 2002

Keywords

  • Arteriogenic
  • Duplex ultrasound
  • Erection
  • PGE
  • Veno-occlusive

ASJC Scopus subject areas

  • Endocrinology

Fingerprint Dive into the research topics of 'Penile pharmacotesting in diagnosing male erectile dysfunction: Evidence for lack of accuracy and specificity'. Together they form a unique fingerprint.

Cite this