Pentacam sensitivity and specificity in detecting occludable angles

Gemma C M Rossi, Luigia Scudeller, Alessio Delfino, Marta Raimondi, Sara Pezzotta, Martina Maccarone, Elena Antoniazzi, Gian Maria Pasinetti, Paolo Emilio Bianchi

Research output: Contribution to journalArticle

Abstract

Purpose. To assess the sensitivity and specificity of Pentacam measurements in detection of occludable angles and to provide cutoff values. Methods. Observational, single-center, cross-sectional study on 64 Caucasian eyes: 28 (43.7%) primary narrow angles or primary angle-closure glaucoma, and 36 (56.2%) controls: all subjects were evaluated and classified by gonioscopy (Shaffer classification). The following measurements have been considered: superior and inferior anterior chamber angle (ACA), temporal and nasal ACA, anterior chamber depth (ACD) using 5 value representation (central, superior, inferior, nasal, temporal), and anterior chamber volume (ACV). Validity of Pentacam parameters to detect patients in Shaffer 0 or I class was assessed by receiver operating characteristic (ROC) curves analysis; cutoffs were chosen as to maximize sensitivity and specificity. Results. All the considered Pentacam measures were statistically different between the 2 groups (p3) allowed correct classification of narrow angles. Conclusions. The study pointed out a high power of Pentacam AVA, ACV, and ACD in detecting occludable angles. Pentacam is simple to use, reliable, and noncontact, provides parameters in a short period, and represents a possible screening tool.

Original languageEnglish
Pages (from-to)701-708
Number of pages8
JournalEuropean Journal of Ophthalmology
Volume22
Issue number5
DOIs
Publication statusPublished - Sep 2012

    Fingerprint

Keywords

  • Angle closure
  • Cutoff value
  • Glaucoma
  • Narrow angle
  • Occludable angle
  • Pentacam
  • Sensitivity
  • Specificity

ASJC Scopus subject areas

  • Ophthalmology

Cite this