Abstract
We present the cytogenetic pattern of a leukemic infant with Diamond-Blackfan anemia (DBA). The karyotype was characterized by clonal evolution involving consecutive gains of chromosome 21 up to pentasomy. No chromosomal changes were present in normal lymphocytes. Such a karyotype evolution has been described in some cases of acute leukemia associated with Down Syndrome, but rarely in non-Down cases.
Original language | English |
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Pages (from-to) | 70-72 |
Number of pages | 3 |
Journal | Cancer Genetics and Cytogenetics |
Volume | 63 |
Issue number | 1 |
DOIs | |
Publication status | Published - Oct 1 1992 |
ASJC Scopus subject areas
- Cancer Research
- Genetics
- Molecular Biology