The aim of this study was to re-evaluate the overall prevalence of peptic disease in 350 patients with liver diseases of different etiology and severity. A normal endoscopic picture was found in 82% of cases. Peptic lesions were found in 18% of the cases and were located in the duodenal (10.9%) and gastric (7.1%) wall. On the basis of a 15 - 20% rate, which most authors think to be a reasonable estimate of the overall ulcer prevalence in the normal population, the prevalence rate in this survey would suggest that there is no association between ulcer and liver disease. Ulcers were more commonly present in cirrhotic than in noncirrhotic patients. Both alcohol intake and cigarette smoking were identified as two ulcerogenic events in these patients while portal hypertension and etiology of liver disease were irrelevant factors. The simultaneous occurence of the three ulcerogenic factors (cirrhosis, smoking, and alcohol intake) in a given patient seems to potentiate each factor as an ulcerogenic event. It is concluded that patients with liver diseases share the same risk of developing a peptic disease as the general population.
|Translated title of the contribution||Peptic ulcer prevalence in patients with different liver diseases|
|Number of pages||5|
|Publication status||Published - 1986|
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