TY - JOUR
T1 - Peptide Patterns as Discriminating Biomarkers in Plasma of Patients With Familial Adenomatous Polyposis
AU - Agatea, Lisa
AU - Crotti, Sara
AU - Ragazzi, Eugenio
AU - Bedin, Chiara
AU - Urso, Emanuele
AU - Mammi, Isabella
AU - Traldi, Pietro
AU - Pucciarelli, Salvatore
AU - Nitti, Donato
AU - Agostini, Marco
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Micro-Abstract We use the mass spectrometry technique for the detection of circulating peptides in patients with familial adenomatous polyposis (FAP). We describe a FAP-specific fingerprint that allows early identification of the disease and neoplastic transformation. Our results are relevant because they could postpone preventive surgery as long as possible, improving the quality of life of patients with FAP.
AB - Micro-Abstract We use the mass spectrometry technique for the detection of circulating peptides in patients with familial adenomatous polyposis (FAP). We describe a FAP-specific fingerprint that allows early identification of the disease and neoplastic transformation. Our results are relevant because they could postpone preventive surgery as long as possible, improving the quality of life of patients with FAP.
KW - Circulating plasma peptides
KW - Colon cancer
KW - Complement system C3f
KW - Matrix-assisted laser desorption/ionization
KW - Switch adenoma-carcinoma
UR - http://www.scopus.com/inward/record.url?scp=84953775221&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84953775221&partnerID=8YFLogxK
U2 - 10.1016/j.clcc.2015.12.002
DO - 10.1016/j.clcc.2015.12.002
M3 - Article
AN - SCOPUS:84953775221
VL - 15
SP - e75-e92
JO - Clinical Colorectal Cancer
JF - Clinical Colorectal Cancer
SN - 1533-0028
IS - 3
ER -