Percutaneous closure of a paravalvular prosthetic mitral leak complicated by need for acute hemodialysis

Fabiola Sozzi, Nicolas Hugues, Marco Schiavone, Frank Levy, Filippo Civaia, Laura Iacuzio, Philippe Rossi, Stefano Carugo, Francois Bourlon, Armand Eker

Research output: Contribution to journalArticlepeer-review


A case of a severe paravalvular mechanical mitral prosthesis leak (PVL) in a high-risk surgical patient, complicated with acute heart failure at presentation is described. Considering the high surgical risk and the specific echocardiographic features that would prevent the interventional cardiologist to have a direct access to the PVL with a traditional vascular plug or duct occluder, a percutaneous PVL closure with an Amplatzer-Amulet (Abbott, Abbott Park, Illinois, United States) LAA device (28 mm) was chosen for the contiguity of the PVL to the left atrial appendage (LAA). A new-onset hemolysis post-PVL closure and severe renal failure requiring hemodialysis occurred after the procedure, treated with surgical device removal and leak suture. To the best of our knowledge, this is the first case that describes the attempt to close a PVL, contiguous to the LAA, using the Amulet device. The attempt to close a PVL with these features with an Amplatzer-Amulet device, although promising, does not appear completely safe to reach the goal, as in our case. In our opinion, the most important reasons are that specific technical recommendations and broad experiences are lacking. Indeed, specific outcomes of this kind of approach are, to date, still unknown.

Original languageEnglish
Pages (from-to)172-175
JournalJournal of Clinical Ultrasound
Issue number2
Publication statusPublished - 2022


  • Amulet-Amplatzer device
  • paravalvular leak
  • percutaneous closure
  • prosthetic mitral valve

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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