Percutaneous ethanol injection efficacy in the treatment of large symptomatic thyroid cystic nodules: Ten-year follow-up of a large series

S. Del Prete, G. Facchini, R. Rossiello, Alberto Abbruzzese, E. Capasso, M. Caraglia, D. Russo, G. Vitale, G. Giuberti, M. Marra, A. M. D'Alessandro, G. Lupoli, R. Addeo

Research output: Contribution to journalArticlepeer-review

Abstract

We present a prospective study on the long-term efficacy of percutaneous ethanol injection (PEI) treatment of a large series of symptomatic thyroid cystic nodules (STCN). Ninety-eight patients (72 females and 26 males) were treated. The mean basal volume of the STCN was 35.3 mL. In 92 of 98 patients PEI treatment induced a greater than 50% nodule shrinkage, only 6 of 92 responder patients relapsed at a follow-up of 9 years. Moreover, all the patients had a significant clinical benefit because a significant reduction of the cyst-associated symptoms was recorded. Furthermore, a limited number of sessions was required for the treatment of cysts larger than 40 mL (mean ± standard deviation [SD]: 2.7 ± 0.75) demonstrating the feasibility of the procedure also in the treatment of large cysts. In conclusion, PEI is an effective and inexpensive procedure with a high patient compliance and long-lasting effects in the treatment of cysts larger than 40 mL.

Original languageEnglish
Pages (from-to)815-821
Number of pages7
JournalThyroid
Volume12
Issue number9
Publication statusPublished - Sep 2002

ASJC Scopus subject areas

  • Endocrinology

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