Percutaneous transluminal therapeutic ultrasound for high-risk thrombus-containing lesions in native coronary arteries

David Brosh, Antonio L. Bartorelli, Alain Cribier, Juan Mesa, Luis Calderon, Thomas Martyn, Franz Amann, Alberto Sampaolesi, Walter Desmet, Jean Fajadet, Uri Rosenschein

Research output: Contribution to journalArticlepeer-review

Abstract

We assessed the short-term outcome of percutaneous coronary ultrasound thrombolysis (CUT) for high-risk thrombus-containing lesions in native coronaries in the setting of acute coronary syndromes (ACS). Data were prospectively collected in a multicenter (n = 32) registry of consecutive ACS patients. The study population (n = 126) had mostly (84%) totally occluded vessels. The mean age of clot was 5.7 ± 9.5 days (range, 0-60 days). CUT (41 kHz, 18 W) led to device success in 112 (89%) patients, with a residual stenosis of 69% ± 20%. Adjunct PTCA or stenting was used in 97% of the patients. Procedural success was achieved in 124 (98%) patients, with a final residual stenosis of 6% ± 10%. There were no major adverse clinical events during hospitalization. Ultrasound thrombolysis is a feasible procedure that offers a safe and probably effective adjuvant device solution for the treatment of high-risk, thrombus-containing lesions in the native coronary arteries.

Original languageEnglish
Pages (from-to)43-49
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Volume55
Issue number1
DOIs
Publication statusPublished - 2002

Keywords

  • Acolysis
  • Acute coronary syndromes
  • Coronary ultrasound thrombolysis
  • Percutaneous coronary intervention
  • Thrombotic lesion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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