Percutaneous umbilical blood sampling

Indication changes and procedure loss rate in a nine years' experience

M. Buscaglia, L. Ghisoni, M. Bellotti, E. Ferrazzi, P. Levi-Setti, A. M. Marconi, A. Taglioretti, P. Zamperini, G. Pardi

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

A 9 years' experience with percutaneous umbilical blood sampling (PUBS) has been appraised. A total number of 1,272 procedures have been performed in our institution between 1986 and 1994; 861 before the 24th week of gestation and 411 after 24 weeks. The indications for PUBS changed throughout these years because of the rapid evolution of molecular biology and because of the fact that certain conditions can now be diagnosed at earlier stages of gestation by chorionic villi sampling and amniocentesis. Sampling at a later gestational age reflected changes in indications. PUBS loss rate has been calculated for 482 fetuses less than 24 weeks, retrospectively found to be negative for the suspected condition and has been related to gestational age, duration of the procedure and number of needle insertions. Total procedure-related loss rate was 2.3%: 1.6% intrauterine fetal deaths within 48 h of the procedure and 0.7% spontaneous abortions in the 2 weeks following the procedure. Gestational age at the time of the procedure and duration of the procedure were significantly related to fetal losses within 48 h.

Original languageEnglish
Pages (from-to)106-113
Number of pages8
JournalFetal Diagnosis and Therapy
Volume11
Issue number2
Publication statusPublished - 1996

Fingerprint

Cordocentesis
Gestational Age
Chorionic Villi Sampling
Pregnancy
Fetal Death
Amniocentesis
Spontaneous Abortion
Needles
Molecular Biology
Fetus

Keywords

  • Indications
  • Percutaneous umbilical blood sampling
  • Prenatal diagnosis
  • Risks

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Buscaglia, M., Ghisoni, L., Bellotti, M., Ferrazzi, E., Levi-Setti, P., Marconi, A. M., ... Pardi, G. (1996). Percutaneous umbilical blood sampling: Indication changes and procedure loss rate in a nine years' experience. Fetal Diagnosis and Therapy, 11(2), 106-113.

Percutaneous umbilical blood sampling : Indication changes and procedure loss rate in a nine years' experience. / Buscaglia, M.; Ghisoni, L.; Bellotti, M.; Ferrazzi, E.; Levi-Setti, P.; Marconi, A. M.; Taglioretti, A.; Zamperini, P.; Pardi, G.

In: Fetal Diagnosis and Therapy, Vol. 11, No. 2, 1996, p. 106-113.

Research output: Contribution to journalArticle

Buscaglia, M, Ghisoni, L, Bellotti, M, Ferrazzi, E, Levi-Setti, P, Marconi, AM, Taglioretti, A, Zamperini, P & Pardi, G 1996, 'Percutaneous umbilical blood sampling: Indication changes and procedure loss rate in a nine years' experience', Fetal Diagnosis and Therapy, vol. 11, no. 2, pp. 106-113.
Buscaglia, M. ; Ghisoni, L. ; Bellotti, M. ; Ferrazzi, E. ; Levi-Setti, P. ; Marconi, A. M. ; Taglioretti, A. ; Zamperini, P. ; Pardi, G. / Percutaneous umbilical blood sampling : Indication changes and procedure loss rate in a nine years' experience. In: Fetal Diagnosis and Therapy. 1996 ; Vol. 11, No. 2. pp. 106-113.
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