TY - JOUR
T1 - Percutaneous Vertebral Augmentation in Metastatic Disease
T2 - State of the Art
AU - Tancioni, Flavio
AU - Lorenzetti, Martin A.
AU - Navarria, Pierina
AU - Pessina, Federico
AU - Draghi, Riccardo
AU - Pedrazzoli, Paolo
AU - Scorsetti, Marta
AU - Alloisio, Marco
AU - Santoro, Armando
AU - Rodriguez y Baena, Riccardo
PY - 2011/1
Y1 - 2011/1
N2 - Improvements in diagnosis and treatment have prolonged cancer survival, with a consequent increase in the incidence of spinal metastases and vertebral compression fractures with associated axial pain, progressive radiculomyelopathy, and mechanical instability. Pain relief in malignant vertebral compression fractures is key to achieving a better quality of life in patients under palliative care. The gold standard for pain relief is nonsteroidal anti-inflammatory drugs and opioids. Nonresponsive cases are then treated with radiotherapy, which may require 2-4 weeks to take effect and in most cases does not provide complete pain relief. Percutaneous vertebroplasty and percutaneous kyphoplasty can in particular give relief in patients with vertebral body compression fractures that do not cause neurological deficits but severely compromise quality of life because of intractable pain.
AB - Improvements in diagnosis and treatment have prolonged cancer survival, with a consequent increase in the incidence of spinal metastases and vertebral compression fractures with associated axial pain, progressive radiculomyelopathy, and mechanical instability. Pain relief in malignant vertebral compression fractures is key to achieving a better quality of life in patients under palliative care. The gold standard for pain relief is nonsteroidal anti-inflammatory drugs and opioids. Nonresponsive cases are then treated with radiotherapy, which may require 2-4 weeks to take effect and in most cases does not provide complete pain relief. Percutaneous vertebroplasty and percutaneous kyphoplasty can in particular give relief in patients with vertebral body compression fractures that do not cause neurological deficits but severely compromise quality of life because of intractable pain.
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U2 - 10.1016/j.suponc.2011.01.001
DO - 10.1016/j.suponc.2011.01.001
M3 - Article
C2 - 21465731
AN - SCOPUS:79955962489
VL - 9
SP - 4
EP - 10
JO - Journal of Supportive Oncology
JF - Journal of Supportive Oncology
SN - 1544-6794
IS - 1
ER -